Losev R Z, Kulikova A N
Angiol Sosud Khir. 2005;11(3):14-20.
Today diabetes mellitus is one of the most important problems of modern medicine. This review provides an analysis of the reported data on the problem of vascular lesion in patients with diabetes mellitus. The authors consider the problems of diabetes mellitus epidemiology and the incidence of vascular pathology in patients with disorders of carbohydrate metabolism. Introduced the characteristics of the main etiopathogenetic aspects of the origination of diabetic angiopathies with regard to the latest studies into the given subject matter. Special attention is focused on the development of atherosclerotic lesion of lower limb arteries in the presence of diabetes mellitus. The authors review the most important causes of initiation and activation of the process of vessel wall lesion and formation of atherosclerotic plaques in diabetic patients. The study of risk factors of vascular pathology with delineation of the most substantial ones is of paramount importance for both prevention and sound pathogenetic treatment of the given pathology as well as for refinement of the results of surgical treatment of atherosclerotic occlusions associated with diabetes mellitus.
如今，糖尿病是现代医学最重要的问题之一。本综述对已报道的糖尿病患者血管病变问题的数据进行了分析。作者探讨了糖尿病流行病学问题以及碳水化合物代谢紊乱患者血管病变的发生率。介绍了关于糖尿病血管病变发生的主要病因学方面的特点，这是基于对该主题的最新研究。特别关注糖尿病患者下肢动脉粥样硬化病变的发展。作者回顾了糖尿病患者血管壁病变过程启动和激活以及动脉粥样硬化斑块形成的最重要原因。研究血管病变的危险因素并确定其中最主要的因素，对于预防和合理的病因治疗这种疾病，以及改善与糖尿病相关的动脉粥样硬化闭塞的手术治疗结果至关重要。
