Hauth E A M, Stattaus J, Forsting M
Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum, Essen.
Radiologe. 2007 Jul;47(7):628, 630-4. doi: 10.1007/s00117-005-1329-4.
In this prospective study we applied both the bidimensional WHO method and the unidimensional RECIST method in treatment follow-up of solid tumors.
Computed tomography was performed in 80 patients before and after one chemotherapy cycle: 20 patients each with lung cancer, lymphoma, and metastases of the lung and the liver. In 207 tumor lesions unidimensional and bidimensional measurements were performed: 36 lesions of lung cancer, 51 lesions of lymphoma, and 60 lesions of metastases of the lung and the liver, respectively. We assigned the results to the corresponding response categories.
For tumor assessment, the kappa statistic produced a high agreement of 0.94 between the two methods for assessment of therapeutic response.
The unidimensional RECIST measurement is easier to perform in order to assess tumor size during treatment follow-up in oncologic radiology.
在这项前瞻性研究中，我们将世界卫生组织（WHO）的二维方法和单维度实体瘤疗效评价标准（RECIST）方法应用于实体瘤治疗随访。
80例患者在一个化疗周期前后接受了计算机断层扫描：其中肺癌、淋巴瘤、肺转移瘤和肝转移瘤患者各20例。对207个肿瘤病灶进行了单维度和二维测量：分别为36个肺癌病灶、51个淋巴瘤病灶和60个肺及肝转移瘤病灶。我们将结果归入相应的反应类别。
对于肿瘤评估，两种方法在评估治疗反应方面的kappa统计量显示出高度一致性，为0.94。
在肿瘤放射学的治疗随访中，单维度RECIST测量在评估肿瘤大小方面更容易实施。
