冠状动脉旁路移植术对心脏副交感神经功能的影响。

Effect of coronary artery bypass grafting on cardiac parasympathetic nervous function.

作者信息

Niemelä M J, Airaksinen K E, Tahvanainen K U, Linnaluoto M K, Takkunen J T

机构信息

Department of Medicine, Oulu University Central Hospital, Finland.

出版信息

Eur Heart J. 1992 Jul;13(7):932-5. doi: 10.1093/oxfordjournals.eurheartj.a060295.

DOI:10.1093/oxfordjournals.eurheartj.a060295

PMID:1644084

Abstract

Low heart rate variability (HRV) is a predictor of a poor outcome after myocardial infarction. To determine whether coronary artery bypass grafting (CABG) has any effect on HRV, the power spectrum components of HRV were measured in 35 patients before, and 1 week after, CABG. Significant attenuation of all spectral components of HRV were found after CABG (P less than 0.001). High frequency (HF) power decreased to one third of the preoperative level, mid-frequency (MF) power to as little as one fifteenth and low frequency (LF) power to one seventh of the preoperative level. No significant restoration in MF or HF powers occurred during the 6-week follow-up period. The results suggest that CABG causes a marked attenuation of HRV. The prognostic significance of this attenuation is not known.

摘要

低心率变异性（HRV）是心肌梗死后预后不良的一个预测指标。为了确定冠状动脉旁路移植术（CABG）对HRV是否有任何影响，在35例患者冠状动脉旁路移植术前及术后1周测量了HRV的功率谱成分。冠状动脉旁路移植术后发现HRV的所有频谱成分均有显著衰减（P<0.001）。高频（HF）功率降至术前水平的三分之一，中频（MF）功率降至术前水平的十五分之一，低频（LF）功率降至术前水平的七分之一。在6周的随访期内，MF或HF功率没有显著恢复。结果表明，冠状动脉旁路移植术会导致HRV显著衰减。这种衰减的预后意义尚不清楚。