Hossen A, Jaju D, Al-Abri M, Al-Sabti H, Mukaddirov M, Hassan M, Al-Hashmi K
Department of Electrical & Computer Engineering, College of Engineering, Sultan Qaboos University, Oman.
Department of Physiology, College of Medicine, Sultan Qaboos University, Oman.
Technol Health Care. 2017;25(2):197-210. doi: 10.3233/THC-161260.
Myocardial revascularization by coronary artery bypass grafting (CABG) is an effective measure for reducing symptoms and mortality in patients with unstable or severe coronary artery disease (CAD). Autonomic function can be estimated non-invasively using heart rate variability (HRV). HRV of patients undergoing CABG is investigated before and after CABG using a soft-decision wavelet based spectral analysis.
The main purpose of this work is to evaluate non-invasively HRV in patients undergoing CABG before operation; and to monitor the status of patients through HRV investigation on day 6 and day 30 after the CABG operation. The study intends to contribute scientific value to understanding the effect of CABG on the cardiovascular autonomic function and surgical outcome.
The soft-decision wavelet-based technique is used in this work in order to measure the power spectral density of the three main bands (VLF, LF, and HF) of HRV in 24 patients undergoing CABG operation, before the operation (Group 1: G1), and 6 days after operation (Group 2: G2) and 30 days after operation (Group 3: G3). The data is obtained from Sultan Qaboos University hospital in Oman.
The HF power increases in 22 out of 24 patients in G2 compared to G1. While the LF power decreases in 21 out of 24 patients in G2 compared to G1. Comparing G3 to G1 the LF power decreases in 20 patients. The sum of the VLF and LF power is reduced in G2 in all 24 subjects compared to G1, and in 19 subjects in G3 compared to G1.
The power spectral density of the HF shows increase in patients recorded on day 6 after operation compared to patients before the operation. The LF shows a decrease in G2 compared to G1. The results of G3 after 30 days of operation still show an increase of the HF power and a decrease in the LF power in most of the patients compared to their values before operation.
冠状动脉旁路移植术（CABG）进行心肌血运重建是降低不稳定型或重度冠状动脉疾病（CAD）患者症状和死亡率的有效措施。自主神经功能可通过心率变异性（HRV）进行无创评估。本研究采用基于软决策小波的频谱分析方法，对接受CABG手术的患者术前及术后的HRV进行研究。
本研究的主要目的是术前无创评估接受CABG手术患者的HRV，并通过术后第6天和第30天的HRV调查监测患者状态。该研究旨在为理解CABG对心血管自主神经功能和手术结果的影响提供科学价值。
本研究采用基于软决策小波的技术，测量24例接受CABG手术患者术前（第1组：G1）、术后6天（第2组：G2）和术后30天（第3组：G3）HRV三个主要频段（VLF、LF和HF）的功率谱密度。数据来自阿曼苏丹卡布斯大学医院。
与G1相比，G2组24例患者中有22例HF功率增加。与G1相比，G2组24例患者中有21例LF功率降低。与G1相比，G3组20例患者LF功率降低。与G1相比，G2组所有24例受试者的VLF和LF功率之和均降低，G3组19例受试者的VLF和LF功率之和也降低。
与术前患者相比，术后第6天记录的患者HF功率谱密度增加。与G1相比，G2组LF功率降低。术后30天G3组的结果仍显示，与术前值相比，大多数患者的HF功率增加，LF功率降低。
