Murawski Marek, Staniszewska-Kuś Jolanta, Rutowski Roman
I Katedra i Klinika Ginekologii i Połoznictwa, Akademii Medycznej we Wrocławiu.
Polim Med. 2005;35(3):11-20.
In the paper there have been evaluated synthetic absorbable surgical sutures--Coated VICRYL, of short time of their resorption in an organism. The valuation concened their usefulness to carrying out the operations of oviducts with use of microsurgical technique. It consisted in determination of biocompatibility degree of analyzed sutures within tubal tissues and also their technical utility to this kind of procedures. The valuation of the surgical sutures was performed on the ground of experimental studies with use of laboratory animals--New Zealand white female rabbits, in which "end-to-end" microsurgical tubal anastomoses were made, with use of analyzed sutures. In further stage, pathomorphological investigations of the animals were performed (in various time after the operation), during which there were conducted microscopic observations of histologic slides derived from tubal anastomoses regions. The purpose of the work was trying to appoint the most adequate suture material for carrying out the operations of oviducts with use of microsurgical technique. It was also an assistance for an operator to take a decission of choice of the proper surgical sutures for surgical treatment of female mechanical infertility and other kind of microsurgical operations which are performed in gynaecology. Generally good technical utility in microsurgical practice of surgical sutures Coated VICRYL--absorbable of short period of their resorption in tissues was stated. They cause the formation of only single peritoneal adhesions, mainly in the regions of tubal anastomoses previously made and produce relatively small tubal tissue reaction, which testifies to high biocompatibility of the sutures, as the implantation material. The analyzed surgical sutures characterize themselves of very good usefulness to microsurgical operations of oviducts.
在该论文中,对合成可吸收外科缝线——涂层薇乔进行了评估,其在生物体内的吸收时间较短。评估涉及其在使用显微外科技术进行输卵管手术中的实用性。这包括确定分析的缝线在输卵管组织内的生物相容性程度以及它们对这类手术的技术实用性。手术缝线的评估是基于对实验动物——新西兰雌性白兔进行的实验研究,在这些兔子身上使用分析的缝线进行了“端端”显微外科输卵管吻合术。在进一步阶段,对动物进行了病理形态学研究(在手术后的不同时间),在此期间对来自输卵管吻合区域的组织切片进行了显微镜观察。这项工作的目的是试图确定最适合使用显微外科技术进行输卵管手术的缝合材料。这也有助于操作人员决定为女性机械性不孕症的手术治疗以及妇科进行的其他显微外科手术选择合适的手术缝线。总体而言,涂层薇乔外科缝线在显微外科实践中具有良好的技术实用性——在组织中吸收期短且可吸收。它们仅导致单个腹膜粘连的形成,主要在先前进行输卵管吻合的区域,并且产生相对较小的输卵管组织反应,这证明了缝线作为植入材料具有高生物相容性。所分析的手术缝线对输卵管显微外科手术具有非常好的实用性。