双核三链螺旋体中的超分子不对称诱导

Supramolecular asymmetric induction in dinuclear triple-stranded helicates.

作者信息

Yeh Robert M, Raymond Kenneth N

机构信息

Department of Chemistry, University of California, Berkeley, California 94720-1460, USA.

出版信息

Inorg Chem. 2006 Feb 6;45(3):1130-9. doi: 10.1021/ic0515711.

DOI:10.1021/ic0515711

PMID:16441123

Abstract

Supramolecular chiral induction has been observed in five dinuclear triple-stranded helicates composed entirely of achiral components. Three different chiral cations were found to be very effective at inducing high levels of enantiomeric enrichment in racemic mixtures of the helicates. The mechanism of intermolecular chiral induction in one cation-helicate pair, s-nic/K6[Ga2L(1)3], has been elucidated through circular dichroism spectroscopy, X-ray crystallography, and one and two-dimensional NMR spectroscopy (s-nic = N-methyl-s-nicotinium, H4L(1) = 1,4-bis(2',3'-dihydroxybenzamido)phenylene).

摘要

在完全由非手性组分构成的五种双核三链螺旋配合物中观察到了超分子手性诱导现象。发现三种不同的手性阳离子在诱导螺旋配合物外消旋混合物中产生高水平对映体富集方面非常有效。通过圆二色光谱、X射线晶体学以及一维和二维核磁共振光谱（s-nic = N-甲基-s-烟碱鎓，H4L(1) = 1,4-双(2',3'-二羟基苯甲酰胺基)亚苯基）阐明了一种阳离子-螺旋配合物对s-nic/K6[Ga2L(1)3]中分子间手性诱导的机制。