Ruzié Christian, Even Pascale, Ricard David, Roisnel Thierry, Boitrel Bernard
Université de Rennes 1, Institut de Chimie, UMR CNRS 6509, Organométalliques et Catalyse, Chimie et Electrochimie Moléculaire, 35042 Rennes Cedex, France.
Inorg Chem. 2006 Feb 6;45(3):1338-48. doi: 10.1021/ic0514703.
A series of tris(2-aminoethylamine) (tren) capped iron(II) porphyrins has been synthesized and characterized and their affinities for dioxygen and carbon monoxide measured. The X-ray structure of the basic scaffold with nickel inserted in the porphyrin is also reported. All the ligands differ by the nature of the group(s) attached to the secondary amine functions of the cap. These various substitutions were introduced to probe if a hydrogen bond with these secondary amine groups acting as the donor could rationalize the high affinity of these myoglobin models. This work clearly indicates that the cage structure of the tren predominates over all the other appended groups with the exception of p-nitrophenol.
一系列由三（2-氨基乙胺）（tren）封端的铁（II）卟啉已被合成与表征，并测定了它们对氧气和一氧化碳的亲和力。还报道了卟啉中插入镍的基本支架的X射线结构。所有配体因连接在封端仲胺官能团上的基团性质不同而有所差异。引入这些不同的取代基是为了探究以这些仲胺基团作为供体的氢键能否解释这些肌红蛋白模型的高亲和力。这项工作清楚地表明，除了对硝基苯酚外，tren的笼状结构比所有其他附加基团更为重要。
