Dagregorio G, Guillet G
Federation of Dermatology and Plastic Surgery, Centre Hospitalo-Universitaire de Poitiers, Rue de la Milétrie, Poitiers Cedex, France.
J Eur Acad Dermatol Venereol. 2006 Feb;20(2):166-9. doi: 10.1111/j.1468-3083.2006.01399.x.
Few articles have been published about hypertensive leg ulcers and their surgical treatment. Since mid of the year 2000, it has been our policy to treat all hypertensive leg ulcers very early with mesh split-thickness skin grafts. The present series consists of 15 patients whose hypertensive leg ulcers, including five bilateral cases, were treated with 20 mesh grafts from 2000 to 2002.
All patients, nine women and six men, had a long history of hypertension. The same surgical procedure was applied to all 15 patients: a complete mechanical debridement of all necrotic tissues, immediately followed by mesh skin grafting.
Patients were discharged from the hospital after an average post-operative period of 16 days. Upon leaving the hospital, the patients had lesions completely healed in 14 of 20 cases. The graft take had been complete after an average period of 14 days. In six cases, one or two very small patches of skin graft had necrosed and complete healing required an additional period of 1 to 3 months. In all 20 cases, pain had disappeared within 1 week from surgery.
All patients were on opioid therapy before surgery. With medical treatment only, hypertensive leg ulcers used to heal after a mean period of 15 months. After surgery, the average healing period was 2 weeks and opioids were stopped within 1 month after surgery.
The review of the present series shows that early mesh grafting of hypertensive leg ulcers is beneficial, because healing is very quick and the pain will disappear quasi-instantly.
关于高血压性腿部溃疡及其手术治疗的文章发表较少。自2000年年中以来,我们的政策是尽早用网状中厚皮片治疗所有高血压性腿部溃疡。本系列包括15例患者,他们的高血压性腿部溃疡(包括5例双侧病例)在2000年至2002年期间接受了20次网状皮片移植治疗。
所有患者,9名女性和6名男性,均有高血压病史。对所有15例患者采用相同的手术方法:彻底机械清创所有坏死组织,随后立即进行网状皮肤移植。
患者术后平均16天出院。出院时,20例中有14例病变完全愈合。平均14天后皮片完全成活。6例中,有1或2小块皮肤移植片坏死,完全愈合需要额外1至3个月。所有20例患者术后1周内疼痛均消失。
所有患者术前均接受阿片类药物治疗。仅采用药物治疗时,高血压性腿部溃疡通常平均15个月后愈合。手术后,平均愈合时间为2周,术后1个月内停用阿片类药物。
本系列回顾表明,高血压性腿部溃疡早期进行网状皮片移植是有益的,因为愈合非常快,疼痛几乎立即消失。