Lombardo Vincenzo Trapani, Sottilotta Gianluca
Hemophilia Center--Thrombosis and Hemostasis Service, Hematology Department, Azienda Ospedaliera Bianchi-Melacrino-Morelli, Reggio Calabria, Italy.
Clin Appl Thromb Hemost. 2006 Jan;12(1):115-6. doi: 10.1177/107602960601200120.
The case of a 41-year-old woman with Glanzmann's thrombasthenia who underwent double dental extraction is presented. In the past, treatments with desmopressin (DDAVP) and tranexamic acid had often unsuccessful efficacy to stop or decrease bleeding. After ineffective DDAVP administration, the removal was performed successfully with recombinant activated factor VII (rFVIIa) infusion. rFVIIa infusion after DDAVP administration could be useful in patients with Glanzmann's thrombasthenia in which DDAVP and tranexamic acid weren't always effective.
本文介绍了一名41岁患有Glanzmann血小板无力症的女性接受两次拔牙手术的病例。过去，使用去氨加压素（DDAVP）和氨甲环酸治疗常常无法有效止血或减少出血。在使用DDAVP无效后，通过输注重组活化因子VII（rFVIIa）成功完成了拔牙手术。对于DDAVP和氨甲环酸并非总是有效的Glanzmann血小板无力症患者，在使用DDAVP后输注rFVIIa可能会有帮助。
