Robinson C M, McQueen M M, Wheelwright E F, Gardner D L, Salter D M
Department of Orthopaedics, Princess Margaret Rose Orthopaedic Hospital, Edinburgh, UK.
Injury. 1992;23(5):300-2. doi: 10.1016/0020-1383(92)90172-o.
In a randomized study of 81 patients with fresh hip fractures who underwent bone biopsy at the time of surgery there was no histologically detectable osteomalacia. This represented a fall in prevalence since a similar study 20 years previously had shown a 12 per cent incidence in the same population. The implications for routine histological screening and measurement of serum bone biochemistry in patients with hip fractures is discussed. The majority of patients in the study group had histologically detectable osteoporosis suggesting that this was an important factor in the aetiology of femoral neck fractures.
在一项对81例新鲜髋部骨折患者的随机研究中，这些患者在手术时接受了骨活检，组织学检查未发现骨软化症。这表明患病率有所下降，因为20年前的一项类似研究显示同一人群中的发病率为12%。本文讨论了对髋部骨折患者进行常规组织学筛查和血清骨生化检测的意义。研究组中的大多数患者组织学检查可发现骨质疏松，提示这是股骨颈骨折病因中的一个重要因素。
