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美国髋部骨折患者中的隐匿性骨软化症

Occult osteomalacia in American (U.S.A.) patients with fracture of the hip.

作者信息

Sokoloff L

出版信息

Am J Surg Pathol. 1978 Mar;2(1):21-30. doi: 10.1097/00000478-197803000-00003.

DOI:10.1097/00000478-197803000-00003
PMID:637186
Abstract

Low-grade osteomalacia, detectable only by quantitative histological measurement, was present in eight of 31 femoral heads from normocalcemia American patients having intracapsular fracture of the hip. The histological changes were of a much lower degree than those observed in overt clinical osteomalacia. Further, regional differences between the osteoid content of the proximal femur and iliac crest were demonstrated in 13 age-matched controls. In these, the osteoid content of the femoral bone averaged only 30% of that in the iliac crest.

摘要

低级别骨软化症仅通过定量组织学测量才能检测到,在31例患有髋关节囊内骨折的血钙正常的美国患者的股骨头中,有8例存在该病症。组织学变化的程度远低于明显临床骨软化症中观察到的变化。此外,在13名年龄匹配的对照中,股骨近端和髂嵴的类骨质含量存在区域差异。其中,股骨的类骨质含量平均仅为髂嵴的30%。

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