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由肠球菌和草绿色链球菌引起的儿童脑膜炎。

Childhood meningitis caused by enterococci and viridans streptococci.

作者信息

Koorevaar C T, Scherpenzeel P G, Neijens H J, Derksen-Lubsen G, Dzoljic-Danilovic G, de Groot R

机构信息

Dept. of Pediatrics, Sophia Children's Hospital, Rotterdam, The Netherlands.

出版信息

Infection. 1992 May-Jun;20(3):118-21. doi: 10.1007/BF01704596.

Abstract

Selected clinical and laboratory parameters were studied respectively in patients with meningitis caused by enterococci and viridans streptococci in an academic children's hospital. During a nine-year period (1981-1989), enterococci or viridans streptococci were isolated from the cerobrospinal fluid (CSF) of 48 patients. In nine of these 48 patients, enterococci or viridans streptococci were the causative agents of meningitis. These nine children constituted 2.0% of 450 patients with bacterial meningitis in this period. All nine children suffered from underlying diseases; neurosurgical procedures were performed in six of these patients, of whom four had ventricular drains. A head trauma preceded the development of meningitis in another patient. Drainage of the lacrimal duct was associated with the development of meningitis in another patients. One child concurrently suffered from severe gastroenteritis. CSF leukocyte count and CSF protein levels were moderately elevated, whereas CSF glucose levels were either slightly decreased or within the normal range. Meningitis due to enterococci or viridans streptococci is seen predominantly in children under the age of one year. Predisposing factors, including neurosurgical procedures, head trauma and severe gastroenteritis, are usually present in these patients. The prognosis for recovery is generally good.

摘要

在一家学术性儿童医院,我们分别对肠球菌和草绿色链球菌所致脑膜炎患者的部分临床及实验室参数进行了研究。在九年期间(1981 - 1989年),从48例患者的脑脊液(CSF)中分离出了肠球菌或草绿色链球菌。在这48例患者中,有9例患者的脑膜炎病因是肠球菌或草绿色链球菌。这9名儿童占该时期450例细菌性脑膜炎患者的2.0%。所有9名儿童均患有基础疾病;其中6例患者接受了神经外科手术,其中4例有脑室引流管。另1例患者在脑膜炎发生前有头部外伤。泪道引流与另1例患者的脑膜炎发生有关。1名儿童同时患有严重的胃肠炎。脑脊液白细胞计数和脑脊液蛋白水平中度升高,而脑脊液葡萄糖水平要么略有下降,要么在正常范围内。肠球菌或草绿色链球菌所致脑膜炎主要见于1岁以下儿童。这些患者通常存在一些易感因素,包括神经外科手术、头部外伤和严重的胃肠炎。恢复预后总体良好。

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