Brennan G P, Hanna R E, Nizami W A
Division of Cell and Experimental Biology, School of Biology and Biochemistry, Queen's University of Belfast, Northern Ireland, U.K.
Int J Parasitol. 1992 Jul;22(4):479-89. doi: 10.1016/0020-7519(92)90149-f.
The lymphatic system of the paramphistome, Gastrodiscoides hominis consists of numerous fluid-filled branches embedded in parenchyma and surrounded by extracellular material and is closely associated with the major organ systems of the fluke. The lymph matrix consists of a cytoplasmic syncytium within which nuclei, mitochondria and various sized granules and membranous structures occur. The granules found throughout the lymph system morphologically resemble autophagosomes and lysosomes. The lymph system provides a storage site for proteins which can be broken down to amino acids via autophagy, for subsequent mobilization and transport to tissues undergoing active protein synthesis. Many branches of the lymph system are surrounded by specialized parenchymal cells referred to as juxta-lymphatic cells. These cells are apparently associated with autophagic degradation of sequestered lymph cytoplasm, which may serve as an additional mechanism for the mobilization and transport of precursor molecules throughout the fluke via the parenchymal network.
同盘吸虫（Gastrodiscoides hominis）的淋巴系统由大量充满液体的分支组成，这些分支嵌入实质组织中，被细胞外物质包围，并与吸虫的主要器官系统密切相关。淋巴基质由细胞质合胞体组成，其中有细胞核、线粒体以及各种大小的颗粒和膜状结构。在整个淋巴系统中发现的颗粒在形态上类似于自噬体和溶酶体。淋巴系统为蛋白质提供了一个储存位点，这些蛋白质可以通过自噬分解为氨基酸，随后被动员并运输到进行活跃蛋白质合成的组织中。淋巴系统的许多分支被称为近淋巴样细胞的特化实质细胞所包围。这些细胞显然与隔离的淋巴细胞质的自噬降解有关，这可能是通过实质网络在整个吸虫中动员和运输前体分子的另一种机制。
