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[华支睾吸虫病肝脏功能复合生化参数分析]

[Analysis of a complex of biochemical parameters of hepatic functions in opisthorchiasis].

作者信息

Bakshtanovskaia I B, Stepanova T F

出版信息

Med Parazitol (Mosk). 2005 Oct-Dec(4):18-21.

Abstract

A complex of biochemical parameters of hepatic functions was analyzed in 170 patients with chronic opisthorchiasis and in 90 apparently healthy dwellers from a region wherein opisthorchiasis is endemic. The activity of aspartate aminotransferase, alanine aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, alpha-amylase, and choline esterase and the serum concentrations of bilirubin, cholesterol, and glucose were studied. A correlation analysis indicated that prolonged Opisthorchis invasion rearranged the system of interactions of the biochemical parameters of the functions of the liver and pancreas. The auxiliary ("local") standards obtained from a study of a group of apparently healthy dwellers from an opisthorchiasis-endemic region may be use to consider the results of individual examinations of patients with chronic opisthorchiasis in order to correct the processes of treatment and rehabilitation.

摘要

对170例慢性后睾吸虫病患者以及90名来自后睾吸虫病流行地区的貌似健康居民的肝脏功能生化参数复合体进行了分析。研究了天冬氨酸转氨酶、丙氨酸转氨酶、γ-谷氨酰转移酶、碱性磷酸酶、α-淀粉酶和胆碱酯酶的活性以及胆红素、胆固醇和葡萄糖的血清浓度。相关分析表明,后睾吸虫的长期侵袭改变了肝脏和胰腺功能生化参数的相互作用系统。从对一组来自后睾吸虫病流行地区的貌似健康居民的研究中获得的辅助(“局部”)标准,可用于考量慢性后睾吸虫病患者的个体检查结果,以便纠正治疗和康复过程。

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