Watson Peter, Montgomery Erwin B
Department of Speech-Language-Hearing Sciences, University of Minnesota, Twin Cities, USA.
Brain Lang. 2006 May;97(2):233-40. doi: 10.1016/j.bandl.2005.11.004. Epub 2006 Jan 30.
Microelectrode recordings of human sensori-motor subthalamic neuronal activity during spoken sentence and syllable-repetition tasks provided an opportunity to evaluate the relationship between changes in neuronal activities and specific aspects of these vocal behaviors. Observed patterns of neuronal activity included a build up of activity in anticipation of the start of the utterance, a marked reduction in activity associated with the start of the utterance, and a burst of activity during the course of the sentence between the noun phrase and the verb phrase. Overall, changes of neuronal activity were more robust for the sentence repetition task. These data suggest that the basal ganglia play a role in generating meaningful speech utterances, which may parallel its role in complex sequential limb movements. It is possible that the basal ganglia play a role in generating the syntactical structure of language.
在口语句子和音节重复任务期间对人类感觉运动丘脑底核神经元活动进行的微电极记录，为评估神经元活动变化与这些发声行为的特定方面之间的关系提供了契机。观察到的神经元活动模式包括：在话语开始前活动增强，与话语开始相关的活动显著减少，以及在句子中名词短语和动词短语之间出现一阵活动。总体而言，句子重复任务中神经元活动的变化更为强烈。这些数据表明，基底神经节在产生有意义的言语表达中发挥作用，这可能与其在复杂的连续肢体运动中的作用相似。基底神经节有可能在生成语言的句法结构中发挥作用。
