环磷酸腺苷结合蛋白的温度敏感性与神经母细胞瘤细胞的生长和分化调控
Temperature sensitivity of cyclic adenosine 3':5'-monophosphate-binding proteins and the regulation of growth and differentiation in neuroblastoma cells.
作者信息
Simantov R, Sachs L
出版信息
J Biol Chem. 1975 May 10;250(9):3236-42.
PMID:164463
Abstract
The apparent association constant (K-a) of cAMP to the binding proteins from resistant and nonresistant cells was 7.4 times 10-7 M-1 and 8.2 times 10-7 M-1, respectively, and the specific activity of cAMP BINDING TO THESE PROTEINS WAS SIMILAR FOR BOTH TYPES OF CELLS.
摘要
环磷酸腺苷（cAMP）与耐药细胞和非耐药细胞中结合蛋白的表观缔合常数（K-a）分别为7.4×10⁻⁷ M⁻¹和8.2×10⁻⁷ M⁻¹，且两种类型细胞中cAMP与这些蛋白结合的比活性相似。
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