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环磷酸腺苷结合蛋白的温度敏感性与神经母细胞瘤细胞的生长和分化调控

Temperature sensitivity of cyclic adenosine 3':5'-monophosphate-binding proteins and the regulation of growth and differentiation in neuroblastoma cells.

作者信息

Simantov R, Sachs L

出版信息

J Biol Chem. 1975 May 10;250(9):3236-42.

PMID:164463
Abstract

The apparent association constant (K-a) of cAMP to the binding proteins from resistant and nonresistant cells was 7.4 times 10-7 M-1 and 8.2 times 10-7 M-1, respectively, and the specific activity of cAMP BINDING TO THESE PROTEINS WAS SIMILAR FOR BOTH TYPES OF CELLS.

摘要

环磷酸腺苷（cAMP）与耐药细胞和非耐药细胞中结合蛋白的表观缔合常数（K-a）分别为7.4×10⁻⁷ M⁻¹和8.2×10⁻⁷ M⁻¹，且两种类型细胞中cAMP与这些蛋白结合的比活性相似。

相似文献

1
Temperature sensitivity of cyclic adenosine 3':5'-monophosphate-binding proteins and the regulation of growth and differentiation in neuroblastoma cells.环磷酸腺苷结合蛋白的温度敏感性与神经母细胞瘤细胞的生长和分化调控
J Biol Chem. 1975 May 10;250(9):3236-42.
2
Temperature sensitivity of cyclic-adenosine-3':5'-monophosphate-binding proteins, activity of protein kinases and the regulation of cell growth.环磷酸腺苷结合蛋白的温度敏感性、蛋白激酶活性与细胞生长调控
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Specificity of the action of cAMP agonists in the induction of RI cAMP-binding protein in mouse neuroblastoma cells.
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Binding of cyclic nucleotides with proteins in malignant and adenosine cyclic 3':5'-monophosphate-induced "differentiated" neuroblastoma cells in culture.培养的恶性及腺苷环化3':5'-单磷酸诱导的“分化”神经母细胞瘤细胞中环状核苷酸与蛋白质的结合
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引用本文的文献

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Revertants of an S49 cell mutant that expresses altered cyclic AMP-dependent protein kinase.表达改变的环磷酸腺苷依赖性蛋白激酶的S49细胞突变体的回复突变体。
Mol Cell Biol. 1982 Oct;2(10):1229-37. doi: 10.1128/mcb.2.10.1229-1237.1982.
2
Cholera toxin treatment stimulates tumorigenicity of Rous sarcoma virus-transformed cells.霍乱毒素处理可刺激劳氏肉瘤病毒转化细胞的致瘤性。
Mol Cell Biol. 1984 Dec;4(12):2639-42. doi: 10.1128/mcb.4.12.2639-2642.1984.
3
cAMP antagonizes interleukin 2-promoted T-cell cycle progression at a discrete point in early G1.
环磷酸腺苷（cAMP）在G1早期的一个离散点拮抗白细胞介素2促进的T细胞周期进程。
Proc Natl Acad Sci U S A. 1988 Aug;85(16):6072-6. doi: 10.1073/pnas.85.16.6072.
4
Mutations in cyclic AMP-dependent protein kinase and corticotropin (ACTH)-sensitive adenylate cyclase affect adrenal steroidogenesis.环磷酸腺苷依赖性蛋白激酶和促肾上腺皮质激素（ACTH）敏感的腺苷酸环化酶的突变会影响肾上腺类固醇生成。
Proc Natl Acad Sci U S A. 1979 Apr;76(4):1896-900. doi: 10.1073/pnas.76.4.1896.
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Adenosine 3':5'-cyclic monophosphate-dependence of protein kinase isoenzymes from mouse liver.小鼠肝脏蛋白激酶同工酶对3':5'-环磷酸腺苷的依赖性
Biochem J. 1976 Jul 1;157(1):117-26. doi: 10.1042/bj1570117.
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A structural gene mutation affecting the regulatory subunit of cyclic AMP-dependent protein kinase in mouse lymphoma cells.影响小鼠淋巴瘤细胞中环磷酸腺苷依赖性蛋白激酶调节亚基的一种结构基因突变。
Proc Natl Acad Sci U S A. 1975 Dec;72(12):5051-5. doi: 10.1073/pnas.72.12.5051.