Waksman Ron
Division of Cardiology, Washington Hospital Center, Washington, DC, USA.
J Invasive Cardiol. 2006 Feb;18(2):70-4.
Despite the development and progression of metallic stents, many concerns still remain because of their permanent nature. Although metallic stents are effective in preventing recoil and late restenosis after coronary angioplasty, they continue to have limitations such as stent thrombosis and mismatch of the stent to the vessel size. Thus, the concept of bioabsorbable stents has emerged as an alternative to permanent metal stents. This review will outline concepts, material designs, preclinical, and initial clinical experimental studies with bioabsorbable stents.
尽管金属支架有所发展和进步,但由于其永久性,仍存在许多问题。虽然金属支架在预防冠状动脉血管成形术后的回缩和晚期再狭窄方面有效,但它们仍然存在诸如支架血栓形成以及支架与血管大小不匹配等局限性。因此,可生物吸收支架的概念已作为永久性金属支架的替代方案而出现。本综述将概述可生物吸收支架的概念、材料设计、临床前和初步临床实验研究。