Huizar Jose F, Awasthi Ashish, Kozman Hani
Cardiology Department, SUNY Upstate University Hospital, Syracuse, New York, USA.
J Invasive Cardiol. 2006 Feb;18(2):E99-101.
Fibromuscular dysplasia (FMD) is a noninflammatory, nonatherosclerotic disease of the small- to medium-sized vessels that primarily affects young females in their second to fourth decades of life. Typically, FMD involves the renal and extracranial arteries, but at autopsy, it has also been reported to affect the coronary arteries. However, its association with acute coronary syndromes is not yet well recognized. We describe three cases of FMD that presented with an acute myocardial infarction as the initial manifestation and discuss a specific pattern found in all cases as well as the possible patholophysiologic mechanism responsible for the acute coronary syndrome.
纤维肌发育不良（FMD）是一种影响中小血管的非炎症性、非动脉粥样硬化性疾病，主要累及二三十岁至三四十岁的年轻女性。通常，FMD累及肾动脉和颅外动脉，但尸检报告显示其也可累及冠状动脉。然而，FMD与急性冠状动脉综合征的关联尚未得到充分认识。我们描述了3例以急性心肌梗死为首发表现的FMD病例，并讨论了所有病例中发现的一种特定模式以及导致急性冠状动脉综合征的可能病理生理机制。
