Gebauer Bernhard, Tunn Per-Ulf, Gaffke Gunnar, Melcher Ingo, Felix Roland, Stroszczynski Christian
Department of Radiology, Charité, Medical University Berlin, Campus Buch, Lindenberger Weg 80, Berlin, 13125, Germany.
Cardiovasc Intervent Radiol. 2006 Mar-Apr;29(2):210-5. doi: 10.1007/s00270-004-0166-6.
The purpose of this study was to analyze the clinical outcome of osteoid osteoma treated by thermal ablation after drill opening. A total of 17 patients and 20 procedures were included. All patients had typical clinical features (age, pain) and a typical radiograph showing a nidus. In 5 cases, additional histological specimens were acquired. After drill opening of the osteoid osteoma nidus, 12 thermal ablations were induced by laser interstitial thermal therapy (LITT) (9F Power-Laser-Set; Somatex, Germany) and 8 ablations by radiofrequency ablation (RFA) (RITA; StarBurst, USA). Initial clinical success with pain relief has been achieved in all patients after the first ablation. Three patients had an osteoid osteoma recurrence after 3, 9, and 10 months and were successfully re-treated by thermal ablation. No major complication and one minor complication (sensible defect) were recorded. Thermal ablation is a safe and minimally invasive therapy option for osteoid osteoma. Although the groups are too small for a comparative analysis, we determined no difference between laser- and radiofrequency-induced ablation in clinical outcome after ablation.
本研究的目的是分析钻孔后热消融治疗骨样骨瘤的临床结果。共纳入17例患者及20次手术。所有患者均有典型的临床特征（年龄、疼痛）及显示瘤巢的典型X线片。5例获取了额外的组织学标本。在对骨样骨瘤瘤巢进行钻孔后，12次采用激光间质热疗（LITT）（9F Power-Laser-Set；德国索马特克斯公司）进行热消融，8次采用射频消融（RFA）（美国RITA公司的StarBurst）进行消融。首次消融后所有患者均初步获得了疼痛缓解的临床成功。3例患者分别在3个月、9个月和10个月后出现骨样骨瘤复发，经热消融成功再次治疗。未记录到重大并发症，仅记录到1例轻微并发症（感觉缺失）。热消融是治疗骨样骨瘤的一种安全且微创的治疗选择。尽管样本量过小无法进行对比分析，但我们确定激光诱导消融和射频诱导消融在消融后的临床结果上无差异。
