Gösling T, Probst C, Länger F, Rosenthal H, Brunnemer U, Krettek C
Unfallchirurgische Klinik, Medizinische Hochschule Hannover, Hannover.
Chirurg. 2010 Jul;81(7):657-78; quiz 679-80. doi: 10.1007/s00104-009-1862-1.
Primary bone tumors can be either benign or malignant. Metastization is a characteristic feature of malignant bone tumors. Malignant tumors are characterized by a local aggressive and destructive behavior. The behavior of a tumor is dependent on its entity, the differentiation grade and localization and these factors are of decisive importance for the correct therapy. Even benign tumors can behave very aggressively. Different stages are defined. Patient history and conventional radiographs are the most powerful primary diagnostic tools. Many tumors show typical characteristics and if a malignant lesion is suspected a biopsy should be carried out. Several quality standards have to be respected when making the biopsy. The approach to malignant tumors is always interdisciplinary. Several biological as well as alloplastic reconstruction techniques exist. The treatment of primary malignant bone tumors requires a lot of experience and should only be done in specialized centers.
原发性骨肿瘤可以是良性的,也可以是恶性的。转移是恶性骨肿瘤的一个特征性表现。恶性肿瘤的特点是具有局部侵袭性和破坏性。肿瘤的行为取决于其类型、分化程度和位置,这些因素对正确的治疗起着决定性作用。即使是良性肿瘤也可能表现出很强的侵袭性。肿瘤被分为不同阶段。患者病史和传统X线片是最有力的初步诊断工具。许多肿瘤具有典型特征,如果怀疑是恶性病变,应进行活检。进行活检时必须遵循几个质量标准。对恶性肿瘤的治疗始终需要多学科协作。存在多种生物及异体骨重建技术。原发性恶性骨肿瘤的治疗需要丰富的经验,且应仅在专业中心进行。