Sun Hai-tao, Xue Fu-shan, Zhang Guo-hua, Li Cheng-wen, Li Ping, Liu Kun-peng
Department of Anesthesiology, Plastic Surgery Hospital, CAMS and PUMC, Beijing 100041, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2005 Dec;27(6):712-7.
To compare the hemodynamic responses to orotracheal intubation via fiberoptic bronchoscope (FOB) with conventional orotracheal intubation via direct laryngoscope (DLS) in children under general anesthesia.
Forty-three American Society of Anesthesiologist grade I-II children undergoing the elective plastic surgery and requiring orotracheal intubation were randomly allocated to either the DLS group (n = 20)or the FOB group (n = 23). After standard intravenous anesthetic induction, orotracheal intubation was performed using a DLS or a FOB. Noninvasive systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and rate-pressure product (RPP) were recorded before and after anesthetic induction, at intubation, and 5 minutes after intubation with 1 minute interval.
In the DLS group, SBP, HR, and RPP at intubation increased significantly compared to their postinduction values (P < 0.05),but blood pressure, HR and RPP at intubation didn't differ from their preinduction values. The maximal values of SBP, HR and RPP during the observation (from the beginning of intravenous anesthetic induction to 5 minutes after intubation) were significantly higher than their preinduction values (P < 0.05). In the FOB group, blood pressure, HR and RPP at intubation increased significantly compared to their preinduction and postinduction values (P < 0.05), and the maximal values of blood pressure, HR and RPP during the observation were significantly higher than their preinduction values (P < 0.05). There were no significant differences in blood pressure and RPP at each time point during the observation between the two groups. The HR at intubation were significantly higher in the FOB group than in the DLS group (P < 0.05), but no significant difference was observed in the HR values at other time points during the observation between the two groups. There were also no significant differences in the maximal values of blood pressure, HR and RPP or the times to reach their maximal values between the two groups.
General anesthesia of clinical standard depth can not effectively inhibit the pressor and tachycardiac responses caused by fiberoptic orotracheal intubation in children. As compared with DLS, FOB has no special advantages in preventing the cardiovascular stress responses to orotracheal intubation in children.
比较全身麻醉下儿童经纤维支气管镜(FOB)行口气管插管与经直接喉镜(DLS)行传统口气管插管时的血流动力学反应。
43例美国麻醉医师协会分级为I-II级、需行择期整形手术并需口气管插管的儿童被随机分为DLS组(n = 20)或FOB组(n = 23)。在标准静脉麻醉诱导后,分别使用DLS或FOB进行口气管插管。在麻醉诱导前、诱导后、插管时以及插管后5分钟,每隔1分钟记录无创收缩压(SBP)、舒张压(DBP)、心率(HR)和率压积(RPP)。
在DLS组,插管时的SBP、HR和RPP较诱导后值显著升高(P < 0.05),但插管时的血压、HR和RPP与诱导前值无差异。观察期间(从静脉麻醉诱导开始至插管后5分钟)SBP、HR和RPP的最大值显著高于诱导前值(P < 0.05)。在FOB组,插管时的血压、HR和RPP较诱导前和诱导后值显著升高(P < 0.05),观察期间血压、HR和RPP的最大值显著高于诱导前值(P < 0.05)。两组观察期间各时间点的血压和RPP无显著差异。FOB组插管时的HR显著高于DLS组(P < 0.05),但两组观察期间其他时间点的HR值无显著差异。两组血压、HR和RPP的最大值或达到最大值的时间也无显著差异。
临床标准深度的全身麻醉不能有效抑制儿童纤维支气管镜引导下口气管插管引起的升压和心动过速反应。与DLS相比,FOB在预防儿童口气管插管引起的心血管应激反应方面无特殊优势。