Gaugris Sabine, Sazonov-Kocevar Vasilisa, Thomas Mike
Rutgers University, Piscataway, NJ, USA.
J Asthma. 2006 Jan-Feb;43(1):1-7. doi: 10.1080/02770900500446823.
Asthma (A) and allergic rhinitis (AR) are common conditions with evidence of shared epidemiological and patho-physiological backgrounds. A systematic review of the literature in the last three decades was performed to summarize both the prevalence and the economic burden of concomitant AR in adult patients with asthma. The reported prevalence estimates of concomitant AR in patients with asthma in the United States and in Europe studies is in excess of 50%, with up to 100% prevalence reported in patients with allergic asthma. In these populations, asthma-related medical resource use, including asthma attacks, emergency room visits, physician visits, and prescription medication use, is higher among asthmatic patients with concomitant AR compared to those without AR. These patients also experience more frequent absence from work and decreased productivity. A low prevalence (6.2%) of comorbid AR in people with asthma has been reported in a single study from Asia. A combined treatment strategy as recommended by international guidelines may improve asthma outcomes in asthmatic patients with concomitant AR.
哮喘(A)和变应性鼻炎(AR)是常见疾病,有证据表明它们在流行病学和病理生理背景方面存在共同之处。对过去三十年的文献进行了系统综述,以总结成年哮喘患者中合并AR的患病率和经济负担。在美国和欧洲的研究中,哮喘患者中合并AR的报告患病率估计超过50%,在过敏性哮喘患者中报告的患病率高达100%。在这些人群中,与无AR的哮喘患者相比,合并AR的哮喘患者与哮喘相关的医疗资源使用情况更高,包括哮喘发作、急诊就诊、医生就诊和处方药使用。这些患者还更频繁地缺勤且生产力下降。亚洲的一项单一研究报告称,哮喘患者中合并AR的患病率较低(6.2%)。国际指南推荐的联合治疗策略可能会改善合并AR的哮喘患者的哮喘治疗效果。