Einhorn N, Ling P, Secher D, Strander H
Department of Oncology, Karolinska Hospital, Stockholm, Sweden.
Acta Oncol. 1991;30(3):343-5. doi: 10.3109/02841869109092383.
Twelve patients with advanced condylomata acuminata were treated by systemic human leukocyte interferon (IFN) therapy. Semi-purified and purified preparations were both able to affect condylomatous growth. Treatment of the patients at various periods of their disease resulted in one complete remission, 6 partial remissions, 4 minimal responses while one case showed progressive disease. Side-effects were unexpectedly common in these advanced patients and 4 of them had to stop IFN treatment.
12例晚期尖锐湿疣患者接受了全身性人白细胞干扰素(IFN)治疗。半纯化和纯化制剂均能影响湿疣生长。在疾病的不同阶段对患者进行治疗,结果有1例完全缓解,6例部分缓解,4例有轻微反应,而1例病情进展。在这些晚期患者中,副作用出乎意料地常见,其中4例不得不停止IFN治疗。