Jiménez-Teja Daniel, Hernández-Galán Rosario, Collado Isidro González
Departamento de Química Orgánica, Facultad de Ciencias, Universidad de Cádiz, Apdo. 40, 11510 Puerto Real, Cádiz, Spain.
Nat Prod Rep. 2006 Feb;23(1):108-16. doi: 10.1039/b514891j. Epub 2005 Nov 28.
Structural and synthetic studies of the metabolites isolated from Eutypa lata are reviewed. This fungus is the causative agent of Eutypa dieback disease, also known as eutyposis or dying-arm disease, a perennial canker that affects grapevines and many other woody fruit plants. The review, which encompasses all the literature in this field up to the present and in which 76 references are cited, also includes a detailed study of the biological activity of the metabolites, especially the role of toxins in the development of the plant disease. Some aspects of the synthesis and biosynthesis of these metabolites and related compounds are discussed.
本文综述了从葡萄座腔菌中分离出的代谢产物的结构和合成研究。这种真菌是葡萄座腔菌枯萎病的病原体，该病也被称为葡萄座腔菌病或死枝病，是一种影响葡萄藤和许多其他木本果树的多年生溃疡病。该综述涵盖了该领域截至目前的所有文献，并引用了76篇参考文献，还包括对这些代谢产物生物活性的详细研究，特别是毒素在植物病害发展中的作用。文中还讨论了这些代谢产物及相关化合物的合成和生物合成的一些方面。
