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关于小睡和咖啡因作为应对与夜班相关的睡眠-清醒问题的实际对策的实验室研究和现场研究。

Laboratory and field studies of naps and caffeine as practical countermeasures for sleep-wake problems associated with night work.

作者信息

Schweitzer Paula K, Randazzo Angela C, Stone Kara, Erman Milton, Walsh James K

机构信息

Sleep Medicine and Research Center affiliated with St. John's Mercy Medical Center and St. Luke s Hospital, St. Louis, MO; 2Pacific Sleep Medicine, La Jolla, CA 63017, USA.

出版信息

Sleep. 2006 Jan;29(1):39-50. doi: 10.1093/sleep/29.1.39.

Abstract

STUDY OBJECTIVES

To evaluate the effects of napping, caffeine, and napping plus caffeine on performance and alertness in both laboratory and field settings.

DESIGN

(1) Laboratory Study: parallel-groups design with random assignment to 1 of 4 experimental conditions. (2) Field Study: crossover design.

SETTING

Sleep laboratory and field settings.

PARTICIPANTS

(1) Laboratory Study: 68 healthy individuals; (2) Field Study: 53 shiftworkers who worked nights or rotating shifts.

INTERVENTIONS

(1) Laboratory Study: an evening nap opportunity before the first 2 of 4 consecutive simulated night shifts plus placebo taken all 4 nights, caffeine taken nightly, the combination of the nap and caffeine conditions, or placebo. (2) Field Study: an evening nap on the first 2 of 4 consecutive night shifts plus caffeine taken nightly versus placebo taken nightly without naps.

MEASUREMENTS AND RESULTS

(1) Laboratory Study: Napping, caffeine, and their combination all improved alertness and performance as measured by Maintenance of Wakefulness Test and Psychomotor Vigilance Task, but the combination of napping and caffeine was best in improving alertness. (2) Field Study: Napping plus caffeine improved performance as measured by Psychomotor Vigilance Test and decreased subjective sleepiness in individuals working the night shift.

CONCLUSIONS

Napping plus caffeine helps improve performance and alertness of night-shift workers.

摘要

研究目的

评估小睡、咖啡因以及小睡加咖啡因对实验室和实际工作场景中的表现及警觉性的影响。

设计

(1)实验室研究:平行组设计,随机分配至4种实验条件之一。(2)实际工作场景研究:交叉设计。

地点

睡眠实验室和实际工作场景。

参与者

(1)实验室研究:68名健康个体;(2)实际工作场景研究:53名从事夜班或轮班工作的倒班工人。

干预措施

(1)实验室研究:在连续4次模拟夜班中的前2次之前有一个晚间小睡机会,同时4个晚上都服用安慰剂、每晚服用咖啡因、小睡和咖啡因条件的组合,或安慰剂。(2)实际工作场景研究:在连续4个夜班中的前2个晚上有一个晚间小睡,同时每晚服用咖啡因,与每晚不进行小睡只服用安慰剂进行对比。

测量指标与结果

(1)实验室研究:通过清醒维持测试和精神运动警觉性任务测量,小睡、咖啡因及其组合均能提高警觉性和表现,但小睡和咖啡因的组合在提高警觉性方面效果最佳。(2)实际工作场景研究:通过精神运动警觉性测试测量,小睡加咖啡因可提高从事夜班工作个体的表现,并降低主观嗜睡感。

结论

小睡加咖啡因有助于提高夜班工人的表现和警觉性。

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