Oregon Health and Sciences University, School of Medicine, 3455 SW US Veterans Hospital Road, Mailcode: SN-ORD, Portland, OR 97239, USA.
Sleep, Chronobiology, and Health Laboratory, School of Nursing, Oregon Health & Science University, 3455 SW US Veterans Hospital Road, Mailcode: SN-ORD, Portland, OR 97239, USA; Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, 3455 SW US Veterans Hospital Road, Mailcode: SN-ORD, Portland, OR 97239, USA.
Clin Chest Med. 2022 Jun;43(2):249-259. doi: 10.1016/j.ccm.2022.02.003.
A growing body of evidence has placed an increasing emphasis on how sleep affects health. Not only does insufficient sleep make one subjectively feel worse, but is associated with chronic diseases that are considered epidemics in industrialized nations. This is partly caused by the growing need for prolonged work and social schedules, exemplified by shift work, late-night weekends, and early morning work/school start times (social jetlag). Here, we consider fundamental relationships between the circadian clock and biologic processes and discuss how common practices, such as shift work and social jetlag, contribute to sleep disruption, circadian misalignment, and adverse health outcomes.
越来越多的证据强调了睡眠对健康的影响。睡眠不足不仅会让人主观感觉更糟糕,还与被认为是工业化国家流行病的慢性疾病有关。这在一定程度上是由于对延长工作和社交时间的需求不断增长造成的,例如轮班工作、周末熬夜、早上工作/上学时间早(社交时差)。在这里,我们考虑了生物钟和生物过程之间的基本关系,并讨论了常见的做法,如轮班工作和社交时差,如何导致睡眠中断、昼夜节律失调和不良健康后果。