Morris D J, Molnár K, Longshaw M, Adams A
Institute of Aquaculture, University of Stirling, Stirling FK9 4LA, UK.
Parasitology. 2006 Jun;132(Pt 6):781-90. doi: 10.1017/S0031182005009807. Epub 2006 Feb 3.
Species of the phylum Myxozoa are common parasites of fish and can cause severe losses in cultured species. Although a number of myxozoan life-cycles have now been elucidated, little is known about the biology of these organisms in the fish host. Monoclonal antibody B4 raised to the myxozoan Tetracapsuloides bryosalmonae has been previously noted to react with a number of species infecting fish kidney. We present the results of a survey of 55 myxosporean species that determined that this antibody detects an antigen on the spore surface of 33 of these species in the genera Myxobolus, Sphaerospora and Thelohanellus. However, there appears to be no clear relationship between those spores that contain the MAb B4 reactive antigen and the host or organ in which they are detected. The antigen appears to be synthesized in the plasmodial cytoplasm and is intimately associated with the surface of the spore capsules and, where present, the mucus envelope. The nature of this envelope is further discussed in relation to its formation and distinctive properties.
粘孢子虫门的物种是鱼类常见的寄生虫，可给养殖鱼类造成严重损失。尽管现在已经阐明了一些粘孢子虫的生命周期，但对于这些生物体在鱼类宿主体内的生物学特性却知之甚少。先前已注意到，针对粘孢子虫脑粘体虫产生的单克隆抗体B4可与多种感染鱼肾的物种发生反应。我们展示了一项对55种粘孢子虫物种的调查结果，该调查确定这种抗体可检测到粘体虫属、球孢虫属和泰洛汉虫属中33个物种孢子表面的一种抗原。然而，那些含有单克隆抗体B4反应性抗原的孢子与检测到它们的宿主或器官之间似乎没有明显的关系。该抗原似乎在多核体细胞质中合成，并与孢子囊表面以及（若存在）粘液包膜紧密相关。本文进一步讨论了这种包膜的形成及其独特性质。
