McLaughlin N, Bojanowski M W
Centre Hospitalier de l'Université de Montréal (CHUM)-Hôpital Notre-Dame, Neurosurgery Division, Department of Surgery, Montréal, QC, Canada.
Br J Neurosurg. 2005 Jun;19(3):250-3. doi: 10.1080/02688690500208460.
Aneurysms rarely occur at the choroidal branch of the posterior inferior cerebellar artery (PICA) and their pathogenesis is not well understood. We report such a case and review the literature. A 69-year-old female was admitted for a sudden onset of severe headache with nausea and vomiting. Soon after arrival, she became less responsive. CT of the head revealed an intraventricular haemorrhage (IVH) predominantly in the fourth and third ventricles without subarachnoid hemorrhage and associated with hydrocephalus. Cerebral angiography demonstrated an aneurysm at the choroidal branch of the PICA. The aneurysm was resected through a bilateral suboccipital craniotomy. The patient made a remarkable recovery. The literature describes five other cases of aneurysms arising from a choroidal branch of the PICA. Hypertension was a common finding in this population. In summary, aneurysms arising from a choroidal branch of the PICA are rare. Hypertensive vessel damage might be a major factor in their pathogenesis. We propose that the rupture of a hypertensive aneurysm might account for some isolated spontaneous IVH.
动脉瘤很少发生于小脑后下动脉(PICA)的脉络膜支,其发病机制尚不清楚。我们报告这样一例病例并复习相关文献。一名69岁女性因突发严重头痛伴恶心呕吐入院。入院后不久,她的反应变得迟钝。头颅CT显示主要位于第四和第三脑室的脑室内出血(IVH),无蛛网膜下腔出血,且伴有脑积水。脑血管造影显示PICA脉络膜支有一个动脉瘤。通过双侧枕下开颅手术切除了动脉瘤。患者恢复良好。文献中还描述了另外5例起源于PICA脉络膜支的动脉瘤病例。高血压是这一人群的常见表现。总之,起源于PICA脉络膜支的动脉瘤很罕见。高血压性血管损伤可能是其发病机制中的一个主要因素。我们认为高血压性动脉瘤破裂可能是一些孤立性自发性脑室内出血的原因。