AffylmGUI：用于单通道微阵列数据线性建模的图形用户界面。
affylmGUI: a graphical user interface for linear modeling of single channel microarray data.
作者信息
Wettenhall James M, Simpson Ken M, Satterley Keith, Smyth Gordon K
机构信息
Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Pde, Parkville 3050, Australia.
出版信息
Bioinformatics. 2006 Apr 1;22(7):897-9. doi: 10.1093/bioinformatics/btl025. Epub 2006 Feb 2.
SUMMARY
affylmGUI is a graphical user interface (GUI) to an integrated workflow for Affymetrix microarray data. The user is able to proceed from raw data (CEL files) to QC and pre-processing, and eventually to analysis of differential expression using linear models with empirical Bayes smoothing. Output of the analysis (tables and figures) can be exported to an HTML report. The GUI provides user-friendly access to state-of-the-art methods embodied in the Bioconductor software repository.
AVAILABILITY
affylmGUI is an R package freely available from http://www.bioconductor.org. It requires R version 1.9.0 or later and tcl/tk 8.3 or later and has been successfully tested on Windows 2000, Windows XP, Linux (RedHat and Fedora distributions) and Mac OS/X with X11. Further documentation is available at http://bioinf.wehi.edu.au/affylmGUI CONTACT: keith@wehi.edu.au.
摘要
affylmGUI是一个用于Affymetrix微阵列数据集成工作流程的图形用户界面（GUI）。用户能够从原始数据（CEL文件）开始，进行质量控制和预处理，最终使用带有经验贝叶斯平滑的线性模型进行差异表达分析。分析结果（表格和图形）可以导出到HTML报告中。该GUI为用户提供了对Bioconductor软件库中体现的最新方法的友好访问。
可用性
affylmGUI是一个R包，可从http://www.bioconductor.org免费获取。它需要R版本1.9.0或更高版本以及tcl/tk 8.3或更高版本，并且已在Windows 2000、Windows XP、Linux（RedHat和Fedora发行版）和带有X11的Mac OS/X上成功测试。更多文档可在http://bioinf.wehi.edu.au/affylmGUI获取。联系方式：keith@wehi.edu.au
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