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作为马里亚纳群岛查莫罗人的食物的神经毒性狐蝠。

Neurotoxic flying foxes as dietary items for the Chamorro people, Marianas Islands.

作者信息

Banack Sandra Anne, Murch Susan J, Cox Paul Alan

机构信息

California State University, Fullerton, CA 92834, USA.

出版信息

J Ethnopharmacol. 2006 Jun 15;106(1):97-104. doi: 10.1016/j.jep.2005.12.032. Epub 2006 Feb 7.

DOI:10.1016/j.jep.2005.12.032
PMID:16457975
Abstract

Fanihi -- flying foxes (Pteropus mariannus mariannus, Pteropodidae) -- are a highly salient component of the traditional Chamorro diet. A neurotoxic, non-protein amino acid, beta-methylamino-l-alanine (BMAA) accumulates in flying foxes, which forage on the seeds of Cycas micronesica (Cycadaceae) in Guam's forests. BMAA occurs throughout flying fox tissues both as a free amino acid and in a protein-bound form. It is not destroyed by cooking. Protein-bound BMAA also remains in cycad flour which has been washed and prepared by the Chamorro people as tortillas, dumplings, and thickened soups. Other animals that forage on cycad seeds may also provide BMAA inputs into the traditional Chamorro diet.

摘要

狐蝠——关岛狐蝠(Pteropus mariannus mariannus,狐蝠科)——是查莫罗人传统饮食中非常重要的一部分。一种具有神经毒性的非蛋白质氨基酸,β-甲基氨基-L-丙氨酸(BMAA)在狐蝠体内蓄积,狐蝠以关岛森林中的密克罗尼西亚苏铁(苏铁科)种子为食。BMAA以游离氨基酸和蛋白质结合形式存在于狐蝠的全身组织中。烹饪并不能将其破坏。蛋白质结合形式的BMAA也存在于查莫罗人制作玉米饼、饺子和浓汤时所清洗和准备的苏铁面粉中。其他以苏铁种子为食的动物也可能将BMAA带入查莫罗人的传统饮食中。

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Neurotoxic flying foxes as dietary items for the Chamorro people, Marianas Islands.作为马里亚纳群岛查莫罗人的食物的神经毒性狐蝠。
J Ethnopharmacol. 2006 Jun 15;106(1):97-104. doi: 10.1016/j.jep.2005.12.032. Epub 2006 Feb 7.
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Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam.关岛查莫罗人群体中蓝藻神经毒素的生物放大作用与神经退行性疾病
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The analysis of underivatized β-Methylamino-L-alanine (BMAA), BAMA, AEG & 2,4-DAB in Pteropus mariannus mariannus specimens using HILIC-LC-MS/MS.使用亲水相互作用液相色谱-串联质谱法(HILIC-LC-MS/MS)分析马里亚纳狐蝠(Pteropus mariannus mariannus)标本中的未衍生化β-甲基氨基-L-丙氨酸(BMAA)、BAMA、AEG和2,4-二氨基丁酸(2,4-DAB) 。
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Multiple neurotoxic items in the Chamorro diet link BMAA with ALS/PDC.查莫罗人的饮食中的多种神经毒性物质将β-甲基氨基丙氨酸与肌萎缩侧索硬化症/帕金森病痴呆综合征联系起来。
Amyotroph Lateral Scler. 2009;10 Suppl 2:34-40. doi: 10.3109/17482960903278451.

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