Wild John M, Kim Linda S, Pacey Ian E, Cunliffe Ian A
Cardiff School of Optometry and Vision Sciences, Cardiff University, Cardiff, United Kingdom.
Ophthalmology. 2006 Feb;113(2):206-15. doi: 10.1016/j.ophtha.2005.11.002.
To document the magnitude of any learning effect for short-wavelength automated perimetry (SWAP) in patients with either ocular hypertension (OHT) or open-angle glaucoma (OAG) who are experienced in standard automated perimetry (SAP).
Experimental study.
Thirty-five patients (22 with OHT and 13 with OAG) who had previously undergone at least 3 threshold SAP visual field examinations with the Humphrey Field Analyzer (HFA; Carl Zeiss Meditech Inc., Dublin, CA), and 9 patients with OHT who had not previously undertaken any form of perimetry.
Each patient attended for SWAP on 5 occasions, each separated by 1 week. At each visit, both eyes were examined using Program 24-2 of the HFA; the right eye was always examined before the left eye.
(1) Change over the 5 examinations, in each eye, of the visual field indices Mean Deviation (MD), Short-term Fluctuation (SF), Pattern Standard Deviation (PSD), and Corrected Pattern Standard Deviation. (2) Change in each eye between Visits 1 and 5 in proportionate Mean Sensitivity (pMS) for the central annulus of stimulus locations compared with that for the peripheral annulus thereby determining the influence of stimulus eccentricity on any alteration in sensitivity. (3) Change between Visits 1 and 5 in the number and magnitude of the Pattern Deviation (PD) probability levels associated with any alteration in sensitivity.
The MD, SF, and PSD each improved over the 5 examinations (each at P<0.001). The improvement in pMS between Visits 1 and 5 was greater for the peripheral annulus than for the central annulus by approximately twofold for the patients with OAG. Considerable variation was present between patients, within and between groups, in the number of locations exhibiting an improving sensitivity between Visits 1 and 5 by 1 or more PD probability levels.
Care should be taken to ensure that, during the initial examinations, apparent field loss with SWAP in patients exhibiting a normal field by SAP is not the result of inexperience in SWAP. Apparently deeper or wider field loss in the initial examinations with SWAP compared with that exhibited by SAP in OAG also may arise from inexperience in SWAP.
记录在标准自动视野计（SAP）方面有经验的高眼压症（OHT）或开角型青光眼（OAG）患者进行短波长自动视野计（SWAP）时学习效应的程度。
实验研究。
35例患者（22例高眼压症患者和13例开角型青光眼患者），他们之前使用Humphrey视野分析仪（HFA；卡尔蔡司医疗技术公司，加利福尼亚州都柏林）至少进行过3次阈值SAP视野检查，以及9例之前未进行过任何形式视野检查的高眼压症患者。
每位患者分5次进行SWAP检查，每次间隔1周。每次就诊时，使用HFA的24 - 2程序对双眼进行检查；右眼总是在左眼之前检查。
（1）在5次检查中，每只眼睛的视野指数平均偏差（MD）、短期波动（SF）、模式标准差（PSD）和校正模式标准差的变化。（2）与周边环带相比，刺激位置中央环带在第1次和第5次就诊之间的成比例平均敏感度（pMS）变化，从而确定刺激偏心度对敏感度任何改变的影响。（3）第1次和第5次就诊之间与敏感度任何改变相关的模式偏差（PD）概率水平的数量和幅度变化。
MD、SF和PSD在5次检查中均有所改善（每次P<0.001）。对于开角型青光眼患者，第1次和第5次就诊之间周边环带的pMS改善比中央环带大约大两倍。在第1次和第5次就诊之间，敏感度提高1个或更多PD概率水平的位置数量在患者之间、组内和组间存在相当大的差异。
应注意确保在初始检查期间，对于SAP显示视野正常的患者，SWAP中明显的视野缺损不是由于对SWAP不熟练造成的。在开角型青光眼患者中，与SAP相比，SWAP初始检查中明显更深或更宽的视野缺损也可能源于对SWAP不熟练。
