Smith D W, Broom A K, Keil A, Mackenzie J S
Department of Clinical Microbiology, Queen Elizabeth II Medical Centre, Nedlands, WA.
Med J Aust. 1991 Jun 17;154(12):845-6. doi: 10.5694/j.1326-5377.1991.tb121382.x.
To report a recent fatal case of encephalitis associated with evidence of Murray Valley encephalitis virus infection, only the second fatality from this infection in Western Australia.
An 18-month-old Aboriginal boy was admitted to hospital in northwest Western Australia with proven Haemophilus influenzae type b meningitis.
After an initial good response to antibiotics (amoxycillin and cefotaxime) he relapsed and died with evidence of encephalitis. Analysis of serum showed a high titre of antibody to Murray Valley encephalitis (MVE) virus with the presence of specific IgM. No evidence was found for other infective agents.
It is likely that this child died from MVE which followed his bacterial meningitis. Of the strains of mosquitoes trapped in the area of suspected infection 77.8% were Culex annulirostris, the major vector species for MVE. No MVE virus was isolated from these mosquitoes, but serum from one of the sentinel chickens contained MVE virus antibodies, indicating the presence of the virus in that region.
报告一例近期与墨累谷脑炎病毒感染证据相关的致命性脑炎病例，这是西澳大利亚州该感染导致的第二例死亡病例。
一名18个月大的原住民男孩因确诊为b型流感嗜血杆菌脑膜炎被收治于西澳大利亚州西北部的一家医院。
最初对抗生素（阿莫西林和头孢噻肟）治疗反应良好，但之后病情复发并死于脑炎。血清分析显示墨累谷脑炎（MVE）病毒抗体滴度很高且存在特异性IgM。未发现其他感染源的证据。
这名儿童很可能死于细菌性脑膜炎后继发的MVE。在疑似感染区域捕获的蚊子中，77.8%为环喙库蚊，这是MVE的主要传播媒介物种。未从这些蚊子中分离出MVE病毒，但一只哨兵鸡的血清中含有MVE病毒抗体，表明该地区存在该病毒。
