纤维血管内生作为儿童Ahmed青光眼引流阀失败的一个原因。

Fibrovascular ingrowth as a cause of Ahmed glaucoma valve failure in children.

作者信息

Trigler Lucas, Proia Alan D, Freedman Sharon F

机构信息

Dean A. McGee Eye Institute, Oklahoma City, Oklahoma, and Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.

出版信息

Am J Ophthalmol. 2006 Feb;141(2):388-9. doi: 10.1016/j.ajo.2005.08.033.

DOI:10.1016/j.ajo.2005.08.033

PMID:16458704

Abstract

PURPOSE

The purpose of this study is to document the presence of fibrovascular ingrowth into the Ahmed glaucoma valve (AGV) as a cause of AGV failure in the pediatric population.

DESIGN

Retrospective case series.

METHODS

Retrospective study of six children with histologically documented fibrovascular ingrowth of their AGV, with review of relevant demographic, clinical, and surgical factors.

RESULTS

Six patients, two males and four females, with a mean age at AGV placement of 27.5 months (range 1 to 122) were identified with AGV failure, AGV removal, and subsequent histology documenting fibrovascular ingrowth into the valve chamber. Etiology of glaucoma included: trauma, aphakia, angle-closure, aniridia, and infantile. Mean time from AGV implantation to explantation was 23 months (range 6 to 65). Mean intraocular pressure at AGV explantation was 35 mm Hg (range 27 to 48).

CONCLUSIONS

Fibrovascular ingrowth of both the pediatric and adult size AGV occurs in children and should be considered in the presence of AGV failure.

摘要

目的

本研究旨在记录纤维血管长入艾哈迈德青光眼引流阀（AGV）的情况，这是小儿人群中AGV失效的一个原因。

设计

回顾性病例系列研究。

方法

对6例组织学证实AGV存在纤维血管长入的儿童进行回顾性研究，同时回顾相关人口统计学、临床和手术因素。

结果

6例患者，2例男性和4例女性，AGV植入时的平均年龄为27.5个月（范围1至122个月），均出现AGV失效、AGV移除，随后的组织学检查证实有纤维血管长入瓣膜腔。青光眼的病因包括：外伤、无晶状体、闭角型、无虹膜和婴幼儿型。AGV植入至取出的平均时间为23个月（范围6至65个月）。AGV取出时的平均眼压为35 mmHg（范围27至48 mmHg）。