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艾哈迈德青光眼引流装置在印度成年人难治性青光眼病例中的疗效。

The efficacy of Ahmed glaucoma valve drainage devices in cases of adult refractory glaucoma in Indian eyes.

作者信息

Parihar Jitendra K S, Vats Devendra P, Maggon Rakesh, Mathur Vijay, Singh Anirudh, Mishra Sanjay K

机构信息

Department of Ophthalmology, Army Hospital (Research and Referral) Cantt -10, Delhi, India.

出版信息

Indian J Ophthalmol. 2009 Sep-Oct;57(5):345-50. doi: 10.4103/0301-4738.55068.

DOI:10.4103/0301-4738.55068
PMID:19700871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2804121/
Abstract

AIM

To evaluate the efficacy of Ahmed glaucoma valve (AGV) drainage devices in cases of adult refractory glaucoma in Indian eyes.

SETTINGS AND DESIGN

Retrospective interventional case series study.

MATERIALS AND METHODS

Fifty two eyes of 32 patients of refractory glaucoma in the age group of 35 to 60 years who underwent AGV implantation with or without concomitant procedures from January 2003 to Jan 2007 were studied. Of these, 46 eyes (88%) had undergone filtering surgery earlier whereas remaining eyes underwent primary AGV implantation following failure of maximal medical therapy. The follow up ranged between 12 months to 48 months

RESULTS

Eighteen eyes (35%) had undergone phacoemulsification with AGV implantation, penetrating keratoplasty (PK) with AGV and intraocular lens (IOL) implantation in 13 eyes (25%), AGV over preexisting IOL in eight eyes (15%). AGV implantation alone was done in six (11%) eyes. Anterior chamber (AC) reconstruction with secondary IOL and AGV was performed in the remaining eyes. The mean intra ocular pressure (IOP) decreased from 36.3 +/- 15.7 mm Hg to 19.6 +/- 9.2 mm Hg. Complete success as per criteria was achieved in 46 eyes (88%). None of the eyes had failure to maintain IOP control following AGV.

CONCLUSION

The AGV resulted in effective and sustained control of IOP in cases of adult refractory glaucoma in intermediate follow up.

摘要

目的

评估艾哈迈德青光眼引流阀（AGV）植入装置对印度成年人难治性青光眼的疗效。

设置与设计

回顾性干预性病例系列研究。

材料与方法

对2003年1月至2007年1月期间32例年龄在35至60岁的难治性青光眼患者的52只眼睛进行了研究，这些患者接受了AGV植入术，部分患者还接受了相关联合手术。其中，46只眼睛（88%）此前接受过滤过手术，其余眼睛在最大药物治疗失败后接受了初次AGV植入。随访时间为12个月至48个月。

结果

18只眼睛（35%）接受了AGV植入联合超声乳化白内障吸除术，13只眼睛（25%）接受了AGV植入联合穿透性角膜移植术（PK）和人工晶状体（IOL）植入，8只眼睛（15%）在已有IOL的基础上植入AGV。6只眼睛（11%）仅接受了AGV植入。其余眼睛进行了二期IOL和AGV植入的前房（AC）重建。平均眼压（IOP）从36.3±15.7毫米汞柱降至19.6±9.2毫米汞柱。46只眼睛（88%）达到了标准定义的完全成功。AGV植入后，无一例眼睛未能维持眼压控制。

结论

在中期随访中，AGV能有效且持续地控制成人难治性青光眼的眼压。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/59ee/2804121/317305d10f0c/IJO-57-345-g011.jpg
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一项长期临床研究，旨在评估难治性新生血管性青光眼病例中，玻璃体内注射雷珠单抗联合房水引流装置（AGV）与初次植入AGV的疗效对比。
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Comparison of silicone and polypropylene Ahmed Glaucoma Valve implants.硅酮和聚丙烯阿赫迈德青光眼引流阀植入物的比较。
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