Sheinin R
Laryngoscope. 1975 Mar;85(3):468-86. doi: 10.1288/00005537-197503000-00004.
Evidence accumulated over a period of 60 years has clearly established that a number of different viruses cause neoplasia (of a broad spectrum) amongst a variety of animals. Although it is known that viruses do produce self-limiting proliferative human diseases, complete verification of a human viral carcinogen remains to be provided. This paper presents an overview of the conceptual and practical tools for the detection of tumor viruses, which have derived from experimental model systems. It indicates how these are being applied to studies of human malignant disease, with special reference to assessing a possible viral etiology for laryngeal cancer.
60年间积累的证据已明确证实，多种不同病毒可在多种动物中引发（广泛的）肿瘤形成。虽然已知病毒确实会引发人类的自限性增殖性疾病，但人类病毒性致癌物仍有待完全证实。本文概述了源自实验模型系统的用于检测肿瘤病毒的概念性和实用性工具。它指出了这些工具如何应用于人类恶性疾病的研究，特别提及评估喉癌可能的病毒病因。
