Zeddini Abdelfatteh, Zermani Rachida, Rammeh Soumaya, Kourda Nadia, Farah Faten, Ben Jilani Sarrah Baltagi
Service d'Anatomie et Cytologie pathologiques, CHU Charles Nicolle, Tunis, Tunisie.
Prog Urol. 2005 Sep;15(4):722-4.
Castleman disease or angiofollicular lymph node hyperplasia is a rare disease of unknown cause with polymorphic clinical features that raises many diagnostic and therapeutic problems. The unifocal, localized, pseudoneoplastic form, first described in 1956, has a good prognosis, but the multifocal form has a more aggressive course. Three histological types have been identified: hyaline vascular, plasma cell and mixed. The authors present a case of hyaline vascular unifocal Castleman disease. A retroperitoneal mass was discovered incidentally during follow-up ultrasound examination in a 38-year-old woman treated for recurrent renal stones. On CT examination, a solid mass measuring 9 x 8 x 6 cm raised a problem of differential diagnosis with other retroperitoneal masses. CT-guided biopsy was inconclusive and the diagnosis was finally established by tumour excision and histological examination. The immediate and subsequent postoperative course was uneventful.
卡斯特尔曼病或血管滤泡性淋巴结增生是一种病因不明的罕见疾病,具有多形性临床特征,引发了许多诊断和治疗问题。1956年首次描述的单灶性、局限性、假性肿瘤形式预后良好,但多灶性形式病程更为侵袭性。已确定三种组织学类型:透明血管型、浆细胞型和混合型。作者报告一例透明血管型单灶性卡斯特尔曼病病例。一名38岁因复发性肾结石接受治疗的女性在随访超声检查中偶然发现腹膜后肿块。CT检查显示一个大小为9×8×6 cm的实性肿块,这引发了与其他腹膜后肿块的鉴别诊断问题。CT引导下活检结果不明确,最终通过肿瘤切除和组织学检查确诊。术后即刻及随后的病程均顺利。