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[驱动力降低与脑功能受损:慢性低血压的新视角]

[Reduced drive and impaired cerebral performance: a new perspective on chronically low blood pressure].

作者信息

Duschek S, Schandry R

机构信息

Department Psychologie, Ludwig-Maximilians-Universität, München.

出版信息

Dtsch Med Wochenschr. 2006 Feb 10;131(6):272-7. doi: 10.1055/s-2006-924962.

DOI:10.1055/s-2006-924962
PMID:16463232
Abstract

The scientific literature on mental impairment in persons with chronically low blood pressure (using WHO criteria) is systematically reviewed within its physiological context. Subjective symptoms related to hypotension, especially tiredness and listlessness have been adequately demonstrated. There are consistent findings demonstrating deficits in cognitive functions, especially in the fields of concentration and memory. Additionally, contrary to the current views, recent studies provide evidence for an impaired regulation of cerebral blood flow and reduced cerebral perfusion. The resulting deficits in brain function are also reflected in EEG findings. These findings indicate that the marginal attention paid to chronic hypotension in research and clinical practice is no longer justified.

摘要

在生理背景下,对有关慢性低血压患者(采用世界卫生组织标准)精神损伤的科学文献进行了系统回顾。与低血压相关的主观症状,尤其是疲劳和无精打采,已得到充分证实。有一致的研究结果表明认知功能存在缺陷,尤其是在注意力集中和记忆方面。此外,与当前观点相反,最近的研究为脑血流调节受损和脑灌注减少提供了证据。由此导致的脑功能缺陷也反映在脑电图检查结果中。这些发现表明,研究和临床实践中对慢性低血压的边缘关注不再合理。

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引用本文的文献

1
Reduced brain perfusion and cognitive performance due to constitutional hypotension.体质性低血压导致脑灌注和认知功能减退。
Clin Auton Res. 2007 Apr;17(2):69-76. doi: 10.1007/s10286-006-0379-7. Epub 2006 Nov 14.