[痛风]

[Gout].

作者信息

Carey Berner I, Dudler J

机构信息

Service de rhumatologie, médecine physique et rehabilitation CHUV, Lausanne.

出版信息

Rev Med Suisse. 2006 Jan 11;2(48):160-2.

PMID:16463802

Abstract

Gout must be regarded as a systemic and chronic disease with potentially serious sequelae. Hyperuricemia is probably an independent risk factor for cardiovascular diseases, at least in high-risk individuals. Nevertheless, current data do not justify for the moment the treatment of asymptomatic hyperuricemia. Finally, if allopurinol remains the only available agent in Switzerland for the treatment of chronic gout, new molecules, like febuxostat and pegylated uricase, are currently being evaluated.

摘要

痛风必须被视为一种具有潜在严重后遗症的全身性慢性疾病。高尿酸血症可能是心血管疾病的独立危险因素，至少在高危个体中如此。然而，目前的数据暂时无法证明对无症状高尿酸血症进行治疗是合理的。最后，如果在瑞士别嘌醇仍然是治疗慢性痛风的唯一可用药物，那么新型分子，如非布索坦和聚乙二醇化尿酸酶，目前正在接受评估。