Lebeau B, Chauveau F M, Brechot J M, de Fenoyl O, Fabre C, Febvre M, Gimbert J L, Laaban J P, Rochemaure J
Service de Pneumologie, Hôpital Saint-Antoine, Paris.
Presse Med. 1991 Apr 20;20(15):686-8.
This retrospective study of 149 patients with small cell lung cancer highlights the value of bronchial endoscopies combined with biopsies for the follow-up of these cases. A control endoscopy performed during the third month showed that macroscopic lesions had completely disappeared in 42 percent of the patients. Each subsequent endoscopy offered a probability rising from 20 to 50 percent of diagnosing a recurrence in the patients explored. Our study particularly demonstrates the usefulness of bronchial biopsy at the initial site of the lesion, even when the bronchial mucosa seems to have returned to normal, since this biopsy is positive in 4.5 percent of the cases.
这项对149例小细胞肺癌患者的回顾性研究突出了支气管内镜检查联合活检在这些病例随访中的价值。在第三个月进行的对照内镜检查显示,42%的患者宏观病变已完全消失。随后的每次内镜检查发现复发的概率在接受检查的患者中从20%上升到50%。我们的研究特别证明了在病变初始部位进行支气管活检的有用性,即使支气管黏膜似乎已恢复正常,因为在4.5%的病例中该活检呈阳性。