Ando Y, Minami H, Nomura F, Sakai S
Department of Internal Medicine, Japanese Red Cross, Nagoya First Hospital.
Respiration. 1994;61(1):58-60. doi: 10.1159/000196306.
Three patients who exhibited endobronchial mucosal bridges that formed at the site of tumor regression following chemotherapy for small cell lung carcinoma are presented. Histopathologic examination showed residual malignant cells in 2 of the 3 patients within the submucosal fibrous tissue and an overlying benign epithelium. Although these mucosal bridges were previously thought to represent a complete remission following chemotherapy or radiotherapy for small cell lung carcinoma, they may, in fact, harbor a residual malignancy under the benign mucosa.
本文报告了3例小细胞肺癌患者,这些患者在化疗后肿瘤消退部位出现了支气管内膜黏膜桥。组织病理学检查显示,3例患者中有2例在黏膜下纤维组织及上方的良性上皮内存在残留的恶性细胞。尽管这些黏膜桥以前被认为是小细胞肺癌化疗或放疗后完全缓解的表现,但实际上,在良性黏膜下可能隐藏着残留的恶性肿瘤。