Matsubara N, Fuchimoto S, Iwagaki H, Nonaka Y, Kimura T, Kashino H, Edamatsu R, Hiramatsu M, Orita K
First Department of Surgery, Okayama University Medical School, Japan.
Res Commun Chem Pathol Pharmacol. 1991 Feb;71(2):239-42.
Among the cytokines which show an antiproliferative effect on certain tumor cells, we investigated the free radical scavenging properties of tumor necrosis factor-alpha, interferon-alpha, and interferon-gamma. The scavenging properties were determined in vitro by the ability to reduce DPPH free radicals. All of these cytokines exhibited marked DPPH free radical scavenging ability.
在对某些肿瘤细胞具有抗增殖作用的细胞因子中,我们研究了肿瘤坏死因子-α、α干扰素和γ干扰素的自由基清除特性。通过还原DPPH自由基的能力在体外测定清除特性。所有这些细胞因子均表现出显著的DPPH自由基清除能力。