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自由基清除特性在细胞因子作用中的可能参与。

The possible involvement of free radical scavenging properties in the actions of cytokines.

作者信息

Matsubara N, Fuchimoto S, Iwagaki H, Nonaka Y, Kimura T, Kashino H, Edamatsu R, Hiramatsu M, Orita K

机构信息

First Department of Surgery, Okayama University Medical School, Japan.

出版信息

Res Commun Chem Pathol Pharmacol. 1991 Feb;71(2):239-42.

PMID:1646468
Abstract

Among the cytokines which show an antiproliferative effect on certain tumor cells, we investigated the free radical scavenging properties of tumor necrosis factor-alpha, interferon-alpha, and interferon-gamma. The scavenging properties were determined in vitro by the ability to reduce DPPH free radicals. All of these cytokines exhibited marked DPPH free radical scavenging ability.

摘要

在对某些肿瘤细胞具有抗增殖作用的细胞因子中,我们研究了肿瘤坏死因子-α、α干扰素和γ干扰素的自由基清除特性。通过还原DPPH自由基的能力在体外测定清除特性。所有这些细胞因子均表现出显著的DPPH自由基清除能力。

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