Groll S, Weidenhammer W, Schmidt A
Institut für Klinische Forschung, Hamburg.
Schweiz Rundsch Med Prax. 1991 May 14;80(20):560-4.
In recent years the importance of the assessment of quality of life increased, especially in palliative therapy. Commonly used concepts of quality of life comprise of several dimensions, e.g. somatic disorders, functional status, well-being and social interaction. We developed an 18-item questionnaire, self-administered by the patients, and compared the results of 66 'healthy' subjects with two clinical samples: 126 patients with inoperable non-small-cell lung cancer and 19 patients under dialysis. The results indicate the questionnaire as a sufficiently reliable and valid method for the assessment of 'quality of life'. On the other hand, there are several problems concerning an adequate interpretation when regarding our clinical data. For example, the cancer patients show a significantly more positive self-assessment concerning well-being and activity, compared to 'healthy' subjects.
近年来,生活质量评估的重要性日益增加,尤其是在姑息治疗中。常用的生活质量概念包括几个维度,例如躯体疾病、功能状态、幸福感和社会互动。我们开发了一份由患者自行填写的包含18个条目的问卷,并将66名“健康”受试者的结果与两个临床样本进行了比较:126例无法手术的非小细胞肺癌患者和19例接受透析的患者。结果表明,该问卷是一种用于评估“生活质量”的足够可靠且有效的方法。另一方面,在看待我们的临床数据时,关于充分解释存在几个问题。例如,与“健康”受试者相比,癌症患者在幸福感和活动方面表现出明显更积极的自我评估。