Nonaka M, Ohno M, Fukuzumi M, Shiojiri Y, Kataoka D, Yamamoto S, Asano M, Ohtake H, Tedoriya T, Kadokura M
First Department of Surgery, Showa University School of Medicine, Tokyo, Japan.
Kyobu Geka. 2006 Jul;59(7):519-28; discussion 528-30.
Quality of life (QOL) of long-term survivors (more than 3 years after surgery) of primary non-small cell lung cancer was studied. QOL was analyzed using European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, 30-Item version 3.0 (QLQ-C30) and Hospital Anxiety and Depression Scale (HADS). Sixty of 91 patients (66%) participated in this study 87 +/- 5 (38-172) months postoperatively. In QLQ-C30, calculated scores of physical (84.0 +/- 2.4), role (81.3 +/- 3.6), cognitive (79.7 +/- 2.6), emotional (86.8 +/- 1.9), and social (91.0 +/- 1.9) functioning, and global QOL (72.6 +/- 2.9) were obtained. Calculated HADS A (anxiety) was 3.3 +/- 0.3 and HADS D (depression) was 4.0 +/- 0.4. Postoperative follow-up duration was correlated with financial impact only. QOL of long-term survivors was influenced by gender histology, marital status, employment status, and academic carrier.
对原发性非小细胞肺癌长期存活者（手术后超过3年）的生活质量进行了研究。使用欧洲癌症研究与治疗组织生活质量问卷30项第3.0版（QLQ-C30）和医院焦虑抑郁量表（HADS）对生活质量进行分析。91例患者中有60例（66%）在术后87±5（38 - 172）个月参与了本研究。在QLQ-C30中，获得了身体功能（84.0±2.4）、角色功能（81.3±3.6）、认知功能（79.7±2.6）、情绪功能（86.8±1.9）、社会功能（91.0±1.9）以及总体生活质量（72.6±2.9）的计算得分。计算得出的HADS A（焦虑）为3.3±0.3，HADS D（抑郁）为4.0±0.4。术后随访时间仅与经济影响相关。长期存活者的生活质量受性别、组织学类型、婚姻状况、就业状况和学术职业的影响。
