Phadke Kishore, Iyengar Arpana, Karthik Srilekha, Kumar Anil, Olakkengil Santosh
Childrens Kidney Care Center, Department of Pediatrics, St. Johns Medical College Hospital, Bangalore 560034, India.
Indian Pediatr. 2006 Jan;43(1):44-8.
A retrospective analysis was done on 47 pediatric renal transplants performed over last 16 years at Bangalore, Karnataka. The median age and weight of the recipients at transplantation were 120 months and 21 kg respectively; male to female ratio was 30 to 17. Twenty two children had underlying glomerular disease and 23 had tubulointerstitial disease. Preemptive transplantation was done in 33.3% of patients, 57.2% received hemodialysis and 9.5% received peritoneal dialysis prior to transplantation. The mean duration of dialysis was 2.6 months. The most common source of donor organ was the mother. Immunosuppression medications included cyclosporine, azathioprine, and corticosteroids. Graft survival at 1 year, 5 years, and 10 years was 80%, 45.8% and 37.5% respectively. Renal transplantation is the most optimal way to manage children with ESRD with satisfactory long term results.
对过去16年在卡纳塔克邦班加罗尔进行的47例小儿肾移植进行了回顾性分析。移植时受者的中位年龄和体重分别为120个月和21千克；男女比例为30比17。22名儿童患有潜在的肾小球疾病，23名患有肾小管间质性疾病。33.3%的患者进行了抢先移植，57.2%的患者在移植前接受了血液透析，9.5%的患者接受了腹膜透析。透析的平均持续时间为2.6个月。供体器官最常见的来源是母亲。免疫抑制药物包括环孢素、硫唑嘌呤和皮质类固醇。1年、5年和10年的移植物存活率分别为80%、45.8%和37.5%。肾移植是治疗终末期肾病儿童的最佳方法，长期效果令人满意。
