Jenny A B, Smith J M, Bernardo K L, Woolsey T A
Department of Neurology and Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri 63110.
Somatosens Mot Res. 1991;8(1):23-6. doi: 10.3109/08990229109144726.
We determined the location of 54 horseradish peroxidase (HRP)-labeled motor cortical neuron synaptic terminals on 17 parvocellular neurons in the monkey red nucleus. Synaptic terminals and their postsynaptic elements were identified and reconstructed, using light- and electron-microscopic techniques, from serial thick and thin sections. Terminals were found on proximal and distal dendrites of small and medium-sized parvocellular neurons, where they formed excitatory synapses. Some were 180 microns from cell somata. Approximately half of the labeled terminals, aside from those located at dendritic origins, were situated strategically at or near dendritic branch points. Since monkey parvocellular neurons show little activity during movement, the obvious next question is this: How and in what way does motor cortex influence these cells?
我们确定了54个辣根过氧化物酶（HRP）标记的运动皮质神经元突触终末在猴红核17个小细胞神经元上的位置。利用光镜和电镜技术，从连续的厚切片和薄切片中识别并重建了突触终末及其突触后成分。在中小型小细胞神经元的近端和远端树突上发现了终末，它们在那里形成兴奋性突触。有些离细胞体有180微米。除了位于树突起始部位的那些标记终末外，大约一半的标记终末战略性地位于树突分支点处或其附近。由于猴小细胞神经元在运动过程中几乎没有活动，接下来显而易见的问题是：运动皮质如何以及以何种方式影响这些细胞？
