Phypers M, Harris T, Power C
Tuberculosis Prevention and Control, Public Health Agency of Canada, Ottawa, Ontario, Canada.
Int J Tuberc Lung Dis. 2006 Jan;10(1):99-103.
In a prospective Canadian cohort of 82 764 patients with tuberculosis (TB), the risk of developing central nervous system manifestations of TB (CNS-TB) (1%) was higher among younger, female, Aboriginal and foreign-born persons (P < 0.005), together with an elevated mortality risk (RR 4.23), compared to controls with only pulmonary TB. TB detection was lower in the CNS-TB group (P < 0.005), while the likelihood of being cured was also reduced (P < 0.005). CNS-TB remains a serious complication of TB in the industrialised world.
在一项针对82764名加拿大结核病患者的前瞻性队列研究中，与仅患有肺结核的对照组相比，年龄较小、女性、原住民和外国出生者发生结核性中枢神经系统表现（CNS-TB）的风险（1%）更高（P<0.005），且死亡风险升高（相对风险4.23）。CNS-TB组的结核病检出率较低（P<0.005），治愈的可能性也降低了（P<0.005）。在工业化国家，CNS-TB仍然是结核病的一种严重并发症。
