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一名26岁患结核病男性的横贯性脊髓炎。

Transverse myelitis in a 26-year-old male with tuberculosis.

作者信息

Harizi Edlira, Shemsi Kledisa, Kola Erisa, Hyseni Fjolla, Kola Ina, Siddique Mohammad Abubaker, Sadeque Jafor, Decka Arlind, Dervishi Migena, Nasir Fareeha, Capi Livia, Ayala Ivan, Ghosh Ammy Shankar, Swarna Sanzida Sharmin, Musa Juna, Ahmetgjekaj Ilir

机构信息

Neurology Department, Regional Hospital Durres, Albania.

General Practitioner Doctor, Tirana, Albania.

出版信息

Radiol Case Rep. 2022 Aug 1;17(10):3669-3673. doi: 10.1016/j.radcr.2022.06.091. eCollection 2022 Oct.

Abstract

Acute transverse myelitis is an inflammatory condition covering the entire cross section of the spinal cord, spreading on two or more vertebral segments, without evidence of a compressive lesion. This shows clinically as an acute or subacute onset of paraparesis, lower limb paresthesia, sensory deficits, and impaired sphincter function. Mycobacterium tuberculosis is exceedingly rare cause of this inflammation, with a mechanism still not fully understood. The main etiologies are thought to be an abnormal activation of the immune system against the neuronal cells of the medulla, direct inoculation of the bacillus, and the toxic effect of the antitubercular medications on the spinal cord. We present the case of a 26-year-old male patient with acute symptoms of transverse myelitis and presence of miliary tuberculosis of the lungs. The purpose of this case report is to put the emphasis on the importance of distinguishing the characteristics of tubercular lesions on imaging modalities, especially on magnetic resonance imaging, in the differential diagnosis of tuberculosis as a rare but profoundly serious cause of acute transverse myelitis.

摘要

急性横贯性脊髓炎是一种累及脊髓整个横断面的炎症性疾病,病变累及两个或更多椎体节段,无压迫性病变证据。临床上表现为急性或亚急性双下肢轻瘫、下肢感觉异常、感觉障碍及括约肌功能受损。结核分枝杆菌是导致这种炎症的极为罕见的病因,其发病机制仍未完全明确。主要病因被认为是免疫系统针对延髓神经细胞的异常激活、杆菌的直接接种以及抗结核药物对脊髓的毒性作用。我们报告一例26岁男性患者,有急性横贯性脊髓炎症状且存在粟粒性肺结核。本病例报告的目的是强调在鉴别诊断中,尤其是在磁共振成像上,区分结核病变特征对于作为急性横贯性脊髓炎罕见但极其严重病因的结核病的重要性。

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