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大量青少年精神科住院患者中尼古丁使用与依赖及其与精神障碍的关联。

Nicotine use and dependence and their association to psychiatric disorders in a large sample of adolescent psychiatric inpatients.

作者信息

Hakko Helinä, Lintunen Janne, Lappalainen Jaakko, Mäkikyrö Taru, Räsänen Pirkko, Timonen Markku

机构信息

Oulu University Hospital, Department of Psychiatry, P.O. Box 26, 90029 OYS, Finland.

出版信息

Addict Behav. 2006 Oct;31(10):1873-80. doi: 10.1016/j.addbeh.2006.01.001. Epub 2006 Feb 8.

Abstract

The purpose of this research was to evaluate the level of nicotine dependence (ND) and to examine its association to psychiatric disorders in a representative clinical sample of adolescent psychiatric inpatients. The modified Fagerstrom Tolerance Questionnaire (mFTQ) was used to assess the level of ND. Psychiatric DSM-IV diagnoses were obtained by using the Schedule for affective disorder and schizophrenia for school-age children (K-SADS-PL). Of the total of 342 inpatients in the study sample, 259 (75.7%) reported to be current smokers. A sum score 6 or higher in the mFTQ, indicating a high level of ND, was found in 37.9% of all smokers. An increased likelihood for high level of ND was associated with substance related disorders (OR 5.1, 95% CI 2.8-9.3), conduct disorder and oppositional defiant disorders (OR 2.4, 95% CI 1.4-4.4). The usefulness of mFTQ in measuring ND among adolescent inpatients is apparent. Therefore, it can be recommended to be used as a routine screening instrument for ND among adolescents hospitalized due to psychiatric disorders.

摘要

本研究的目的是评估尼古丁依赖(ND)水平,并在青少年精神科住院患者的代表性临床样本中检验其与精神障碍的关联。采用改良的Fagerstrom耐受问卷(mFTQ)评估ND水平。通过使用学龄儿童情感障碍和精神分裂症检查表(K-SADS-PL)获得精神科DSM-IV诊断。在研究样本的342名住院患者中,259名(75.7%)报告为当前吸烟者。在所有吸烟者中,37.9%的人在mFTQ中的总分达到6分或更高,表明ND水平较高。ND水平较高的可能性增加与物质相关障碍(比值比5.1,95%置信区间2.8 - 9.3)、品行障碍和对立违抗障碍(比值比2.4,95%置信区间1.4 - 4.4)相关。mFTQ在测量青少年住院患者ND方面的实用性是显而易见的。因此,建议将其用作因精神障碍住院的青少年中ND的常规筛查工具。

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