Lyratzopoulos G, Heller R F, McElduff P, Hanily M, Lewis P
Norfolk, Suffolk and Cambridgeshire Strategic Health Authority, Victoria House, Capital Park, Fulbourn, Cambridge CB1 5XB, UK.
Heart. 2006 Sep;92(9):1198-206. doi: 10.1136/hrt.2005.081042. Epub 2006 Feb 8.
To examine recent time trends in blood pressure (BP), total cholesterol, body mass index (BMI) and current smoking among people in the UK of different deprivation groups.
Repeatable survey.
Primary care-based UK cardiovascular risk factor screening programme (58 Stockport general practices).
37,161 women and 33,977 men aged 35-60 years responding to a screening invitation and with a first screening episode during 1989-99.
There were significant decreasing trends in total cholesterol (-0.06 mmol/l/year, 95% confidence interval (CI) -0.07 to -0.06 for women, -0.07 mmol/l/year, 95% CI -0.07 to -0.06 for men), with a significantly faster drop in more deprived groups (-0.005 mmol/year/increasing deprivation group, 95% CI -0.01 to -0.001 for both sexes). There were decreasing trends in current smoking prevalence (odds ratio (OR) 0.97/year, 95% CI 0.96 to 0.97 for women, OR 0.96/year, 95% CI 0.95 to 0.96 for men) with a significantly slower drop in the more deprived groups (OR 1.01/year/increasing deprivation group, 95% CI 1.00 to 1.01 for both sexes). There were significant increasing trends in BMI (0.11 kg/m(2)/year in women, 95% CI 0.09 to 0.13, 0.10 kg/m(2)/year in men, 95% CI 0.08 to 0.11), with a significantly slower increase in the more deprived groups among men only (-0.02 kg/m(2)/year/increasing deprivation group, 95% CI -0.01 to -0.03). Inequality in BP narrowed among men but widened among women.
Inequalities in risk factors between different deprivation groups may be both widening (smoking, BP in women) and narrowing (total cholesterol, BMI and BP in men). Given baseline inequalities in risk factors levels, these trends suggest that inequalities in cardiovascular disease are likely to persist in the future.
研究英国不同贫困程度人群的血压(BP)、总胆固醇、体重指数(BMI)及当前吸烟情况的近期时间趋势。
可重复调查。
基于初级医疗的英国心血管危险因素筛查项目(斯托克波特的58家全科诊所)。
37161名年龄在35 - 60岁的女性和33977名男性,他们回应了筛查邀请并在1989 - 1999年期间有首次筛查记录。
总胆固醇呈显著下降趋势(女性为-0.06 mmol/l/年,95%置信区间(CI)-0.07至-0.06;男性为-0.07 mmol/l/年,95% CI -0.07至-0.06),贫困程度越高的组下降速度显著更快(男女均为-0.005 mmol/年/贫困程度增加组,95% CI -0.01至-0.001)。当前吸烟率呈下降趋势(女性优势比(OR)为0.97/年,95% CI 0.96至0.97;男性OR为0.96/年,95% CI 0.95至0.96),贫困程度越高的组下降速度显著更慢(男女均为OR 1.01/年/贫困程度增加组,95% CI 1.00至1.01)。BMI呈显著上升趋势(女性为0.11 kg/m²/年,95% CI 0.09至0.13;男性为0.10 kg/m²/年,95% CI 0.08至0.11),仅在男性中,贫困程度越高的组上升速度显著更慢(-0.02 kg/m²/年/贫困程度增加组,95% CI -0.01至-0.03)。男性血压不平等程度缩小,但女性中扩大。
不同贫困程度组之间危险因素的不平等可能既有扩大的情况(吸烟、女性血压),也有缩小的情况(总胆固醇、男性BMI和血压)。考虑到危险因素水平的基线不平等,这些趋势表明心血管疾病的不平等在未来可能会持续存在。