Pongratz D
Friedrich-Baur-Institut der Medizinischen Fakultät an der Neurologischen Klinik und Poliklinik der Ludwig Maximilians Universität München.
Dtsch Med Wochenschr. 2006 Feb 17;131(7):330-6; quiz 337-8. doi: 10.1055/s-2006-932520.
Immunogenic inflammatory myopathies are a heterogeneous group of acquired muscle disorders. Clinical and morphological characteristics are on one side muscle weakness, on the other side inflammatory infiltrates in muscle biopsy. Three main groups of different pathogenesis and course can be subdivided: The treatment of inflammatory myopathies is predominantly based on empiric data. Baseline drugs are Corticosteroids and Immunosuppressives. High dose intravenous Immunoglobulins (IVIG) are an important additional therapeutic possibility, especially in inclusion body myositis.
免疫原性炎性肌病是一组异质性的获得性肌肉疾病。临床和形态学特征一方面表现为肌肉无力，另一方面在肌肉活检中可见炎性浸润。可细分为三种不同发病机制和病程的主要类型：炎性肌病的治疗主要基于经验数据。基础药物是皮质类固醇和免疫抑制剂。大剂量静脉注射免疫球蛋白（IVIG）是一种重要的额外治疗选择，尤其是在包涵体肌炎中。
